Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3399

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3398c and Rv3399 are separated by 22 nucleotidesRv3399 and Rv3400 are separated by 63 nucleotidesRv3400 and Rv3401 are separated by 14 nucleotides Rv3398c: Rv3398c - Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate synthase): dimethylallyltransferase (prenyltransferase) (geranyl-diphosphate synthase) + geranyltranstransferase (farnesyl-diphosphate synthase) (farnesyl-pyrophosphate synthetase) (farnesyl diphosphate synthetase) (FPP synthetase) + farnesyltranstransferase (geranylgeranyl-diphosphate synthase), at 3,815,027 to 3,816,106 Rv3398c Rv3399: Rv3399 - Possible S-adenosylmethionine-dependent methyltransferase, at 3,816,129 to 3,817,175 Rv3399 Rv3400: Rv3400 - Probable hydrolase, at 3,817,239 to 3,818,027 Rv3400 Rv3401: Rv3401 - Conserved protein, at 3,818,042 to 3,820,402 Rv3401 Position (kb) 3816 3817 3818Strain fitness (log2 ratio) -2 -1 0 1at 3816.199 kb on + strandat 3816.224 kb on + strandat 3816.263 kb on + strand, within Rv3399at 3816.482 kb on + strand, within Rv3399at 3816.516 kb on + strand, within Rv3399at 3816.562 kb on + strand, within Rv3399at 3817.038 kb on + strand, within Rv3399at 3817.129 kb on + strandat 3817.129 kb on + strandat 3817.173 kb on + strandat 3817.190 kb on - strandat 3817.201 kb on + strandat 3817.217 kb on + strandat 3817.392 kb on + strand, within Rv3400at 3817.392 kb on + strand, within Rv3400at 3817.393 kb on - strand, within Rv3400at 3817.464 kb on + strand, within Rv3400at 3817.572 kb on + strand, within Rv3400at 3817.572 kb on + strand, within Rv3400at 3817.572 kb on + strand, within Rv3400at 3817.573 kb on - strand, within Rv3400at 3817.573 kb on - strand, within Rv3400at 3817.928 kb on - strand, within Rv3400at 3818.161 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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3,816,199 + +0.1
3,816,224 + -0.8
3,816,263 + Rv3399 0.13 -0.9
3,816,482 + Rv3399 0.34 -0.4
3,816,516 + Rv3399 0.37 -0.9
3,816,562 + Rv3399 0.41 -0.0
3,817,038 + Rv3399 0.87 -0.4
3,817,129 + +0.7
3,817,129 + -0.2
3,817,173 + -0.1
3,817,190 - -0.1
3,817,201 + +1.7
3,817,217 + -0.7
3,817,392 + Rv3400 0.19 -0.7
3,817,392 + Rv3400 0.19 -1.7
3,817,393 - Rv3400 0.20 -1.1
3,817,464 + Rv3400 0.29 -1.4
3,817,572 + Rv3400 0.42 +0.1
3,817,572 + Rv3400 0.42 -1.8
3,817,572 + Rv3400 0.42 -1.0
3,817,573 - Rv3400 0.42 -0.5
3,817,573 - Rv3400 0.42 -0.9
3,817,928 - Rv3400 0.87 -1.9
3,818,161 - +0.2

Or see this region's nucleotide sequence