Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2679

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2678c and Rv2679 are separated by 52 nucleotidesRv2679 and Rv2680 are separated by 159 nucleotidesRv2680 and Rv2681 are separated by 1 nucleotides Rv2678c: Rv2678c - Probable uroporphyrinogen decarboxylase HemE (uroporphyrinogen III decarboxylase) (URO-D) (UPD), at 2,993,989 to 2,995,062 Rv2678c Rv2679: Rv2679 - Probable enoyl-CoA hydratase EchA15 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 2,995,115 to 2,995,945 Rv2679 Rv2680: Rv2680 - Conserved protein, at 2,996,105 to 2,996,737 Rv2680 Rv2681: Rv2681 - Conserved hypothetical alanine rich protein, at 2,996,739 to 2,998,055 Rv2681 Position (kb) 2995 2996Strain fitness (log2 ratio) -1 0 1at 2995.102 kb on + strandat 2995.103 kb on - strandat 2995.123 kb on + strandat 2995.123 kb on + strandat 2995.124 kb on - strandat 2995.622 kb on + strand, within Rv2679at 2995.623 kb on - strand, within Rv2679at 2995.623 kb on - strand, within Rv2679at 2995.625 kb on + strand, within Rv2679at 2995.797 kb on - strand, within Rv2679at 2995.989 kb on + strandat 2996.277 kb on - strand, within Rv2680at 2996.367 kb on - strand, within Rv2680at 2996.402 kb on - strand, within Rv2680at 2996.417 kb on + strand, within Rv2680at 2996.875 kb on + strand, within Rv2681

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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2,995,102 + -0.1
2,995,103 - -0.3
2,995,123 + +0.0
2,995,123 + +0.3
2,995,124 - +0.2
2,995,622 + Rv2679 0.61 -0.7
2,995,623 - Rv2679 0.61 -0.8
2,995,623 - Rv2679 0.61 -0.5
2,995,625 + Rv2679 0.61 -0.3
2,995,797 - Rv2679 0.82 -1.1
2,995,989 + -0.0
2,996,277 - Rv2680 0.27 +0.6
2,996,367 - Rv2680 0.41 -0.5
2,996,402 - Rv2680 0.47 -0.6
2,996,417 + Rv2680 0.49 +0.6
2,996,875 + Rv2681 0.10 -0.7

Or see this region's nucleotide sequence