Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2170

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2168c and Rv2169c are separated by 144 nucleotidesRv2169c and Rv2170 are separated by 265 nucleotidesRv2170 and Rv2171 are separated by 95 nucleotidesRv2171 and Rv2172c overlap by 4 nucleotides Rv2168c: Rv2168c - Putative transposase for insertion sequence element IS6110 (fragment), at 2,431,094 to 2,431,420 Rv2168c Rv2169c: Rv2169c - Probable conserved transmembrane protein, at 2,431,565 to 2,431,969 Rv2169c Rv2170: Rv2170 - GCN5-related N-acetyltransferase, at 2,432,235 to 2,432,855 Rv2170 Rv2171: Rv2171 - Probable conserved lipoprotein LppM, at 2,432,951 to 2,433,634 Rv2171 Rv2172c: Rv2172c - Conserved protein, at 2,433,631 to 2,434,536 Rv2172c Position (kb) 2432 2433Strain fitness (log2 ratio) -1 0 1at 2431.567 kb on - strandat 2431.711 kb on - strand, within Rv2169cat 2432.003 kb on - strandat 2432.051 kb on - strandat 2432.051 kb on - strandat 2432.051 kb on - strandat 2432.071 kb on - strandat 2432.136 kb on + strandat 2432.142 kb on - strandat 2432.142 kb on - strandat 2432.242 kb on + strandat 2432.243 kb on - strandat 2432.304 kb on + strand, within Rv2170at 2432.305 kb on - strand, within Rv2170at 2432.917 kb on + strandat 2432.917 kb on + strandat 2432.921 kb on + strandat 2432.921 kb on + strandat 2432.922 kb on - strandat 2433.188 kb on + strand, within Rv2171at 2433.188 kb on + strand, within Rv2171at 2433.188 kb on + strand, within Rv2171at 2433.427 kb on - strand, within Rv2171

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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2,431,567 - -0.1
2,431,711 - Rv2169c 0.36 -0.4
2,432,003 - -0.3
2,432,051 - -0.9
2,432,051 - -1.3
2,432,051 - -0.2
2,432,071 - -0.4
2,432,136 + +0.8
2,432,142 - +0.1
2,432,142 - +0.1
2,432,242 + -1.1
2,432,243 - -1.4
2,432,304 + Rv2170 0.11 -1.1
2,432,305 - Rv2170 0.11 -0.3
2,432,917 + -1.4
2,432,917 + +1.2
2,432,921 + -0.2
2,432,921 + +0.2
2,432,922 - -0.5
2,433,188 + Rv2171 0.35 -0.0
2,433,188 + Rv2171 0.35 -1.3
2,433,188 + Rv2171 0.35 -0.0
2,433,427 - Rv2171 0.70 -1.7

Or see this region's nucleotide sequence