Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2001

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2000 and Rv2001 are separated by 9 nucleotidesRv2001 and Rv2002 are separated by 75 nucleotidesRv2002 and Rv2003c are separated by 120 nucleotides Rv2000: Rv2000 - Unknown protein, at 2,245,209 to 2,246,822 Rv2000 Rv2001: Rv2001 - Conserved hypothetical protein, at 2,246,832 to 2,247,584 Rv2001 Rv2002: Rv2002 - Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase), at 2,247,660 to 2,248,442 Rv2002 Rv2003c: Rv2003c - Conserved hypothetical protein, at 2,248,563 to 2,249,420 Rv2003c Position (kb) 2246 2247 2248Strain fitness (log2 ratio) -1 0 1at 2245.845 kb on + strand, within Rv2000at 2245.845 kb on + strand, within Rv2000at 2245.845 kb on + strand, within Rv2000at 2245.845 kb on + strand, within Rv2000at 2245.846 kb on - strand, within Rv2000at 2245.953 kb on + strand, within Rv2000at 2245.954 kb on - strand, within Rv2000at 2245.954 kb on - strand, within Rv2000at 2245.996 kb on + strand, within Rv2000at 2245.996 kb on + strand, within Rv2000at 2245.997 kb on - strand, within Rv2000at 2245.997 kb on - strand, within Rv2000at 2246.235 kb on + strand, within Rv2000at 2246.236 kb on - strand, within Rv2000at 2246.379 kb on + strand, within Rv2000at 2246.379 kb on + strand, within Rv2000at 2246.379 kb on + strand, within Rv2000at 2246.382 kb on - strand, within Rv2000at 2246.446 kb on + strand, within Rv2000at 2246.447 kb on - strand, within Rv2000at 2246.549 kb on + strand, within Rv2000at 2246.608 kb on + strand, within Rv2000at 2246.630 kb on - strand, within Rv2000at 2246.776 kb on + strandat 2246.893 kb on - strandat 2246.893 kb on - strandat 2247.409 kb on + strand, within Rv2001at 2247.410 kb on - strand, within Rv2001at 2247.580 kb on + strandat 2247.713 kb on + strandat 2248.376 kb on - strandat 2248.440 kb on + strandat 2248.565 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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2,245,845 + Rv2000 0.39 -0.3
2,245,845 + Rv2000 0.39 -0.3
2,245,845 + Rv2000 0.39 -0.9
2,245,845 + Rv2000 0.39 -0.9
2,245,846 - Rv2000 0.39 -1.1
2,245,953 + Rv2000 0.46 -0.3
2,245,954 - Rv2000 0.46 +0.0
2,245,954 - Rv2000 0.46 +1.0
2,245,996 + Rv2000 0.49 -0.1
2,245,996 + Rv2000 0.49 -0.2
2,245,997 - Rv2000 0.49 +1.0
2,245,997 - Rv2000 0.49 -0.4
2,246,235 + Rv2000 0.64 +1.5
2,246,236 - Rv2000 0.64 -0.4
2,246,379 + Rv2000 0.72 -0.2
2,246,379 + Rv2000 0.72 +0.0
2,246,379 + Rv2000 0.72 -0.5
2,246,382 - Rv2000 0.73 -1.1
2,246,446 + Rv2000 0.77 -0.1
2,246,447 - Rv2000 0.77 -0.9
2,246,549 + Rv2000 0.83 -0.4
2,246,608 + Rv2000 0.87 +0.3
2,246,630 - Rv2000 0.88 +0.1
2,246,776 + +0.3
2,246,893 - -0.6
2,246,893 - -0.0
2,247,409 + Rv2001 0.77 -1.1
2,247,410 - Rv2001 0.77 -0.8
2,247,580 + -0.1
2,247,713 + -0.3
2,248,376 - -0.5
2,248,440 + -0.5
2,248,565 - -0.1

Or see this region's nucleotide sequence