Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1851

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1850 and Rv1851 overlap by 1 nucleotidesRv1851 and Rv1852 are separated by 10 nucleotidesRv1852 and Rv1853 are separated by 7 nucleotides Rv1850: Rv1850 - Urease alpha subunit UreC (urea amidohydrolase), at 2,097,961 to 2,099,694 Rv1850 Rv1851: Rv1851 - Urease accessory protein UreF, at 2,099,694 to 2,100,329 Rv1851 Rv1852: Rv1852 - Urease accessory protein UreG, at 2,100,340 to 2,101,014 Rv1852 Rv1853: Rv1853 - Probable urease accessory protein UreD, at 2,101,022 to 2,101,648 Rv1853 Position (kb) 2099 2100 2101Strain fitness (log2 ratio) -1 0 1at 2098.837 kb on - strand, within Rv1850at 2098.860 kb on - strand, within Rv1850at 2098.860 kb on - strand, within Rv1850at 2099.031 kb on + strand, within Rv1850at 2099.209 kb on + strand, within Rv1850at 2099.523 kb on - strandat 2099.663 kb on + strandat 2099.668 kb on - strandat 2099.680 kb on + strandat 2100.120 kb on + strand, within Rv1851at 2100.169 kb on + strand, within Rv1851at 2100.526 kb on + strand, within Rv1852at 2101.013 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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2,098,837 - Rv1850 0.51 +0.8
2,098,860 - Rv1850 0.52 +1.3
2,098,860 - Rv1850 0.52 -0.2
2,099,031 + Rv1850 0.62 -0.2
2,099,209 + Rv1850 0.72 +0.5
2,099,523 - +1.0
2,099,663 + +0.2
2,099,668 - +0.2
2,099,680 + -0.7
2,100,120 + Rv1851 0.67 -1.2
2,100,169 + Rv1851 0.75 -0.2
2,100,526 + Rv1852 0.28 -0.2
2,101,013 - -0.2

Or see this region's nucleotide sequence