Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1570

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1569 and Rv1570 overlap by 4 nucleotidesRv1570 and Rv1571 overlap by 1 nucleotidesRv1571 and Rv1572c are separated by 145 nucleotidesRv1572c and Rv1573 are separated by 15 nucleotides Rv1569: Rv1569 - Probable 8-amino-7-oxononanoate synthase BioF1 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase), at 1,776,702 to 1,777,862 Rv1569 Rv1570: Rv1570 - Dethiobiotin synthetase BioD, at 1,777,859 to 1,778,539 Rv1570 Rv1571: Rv1571 - Conserved protein, at 1,778,539 to 1,779,048 Rv1571 Rv1572c: Rv1572c - Conserved hypothetical protein, at 1,779,194 to 1,779,298 Rv1572c Rv1573: Rv1573 - Probable PhiRv1 phage protein, at 1,779,314 to 1,779,724 Rv1573 Position (kb) 1777 1778 1779Strain fitness (log2 ratio) -2 -1 0 1at 1777.029 kb on + strand, within Rv1569at 1777.369 kb on + strand, within Rv1569at 1777.370 kb on - strand, within Rv1569at 1777.375 kb on + strand, within Rv1569at 1777.760 kb on + strandat 1778.429 kb on - strand, within Rv1570at 1778.429 kb on - strand, within Rv1570at 1779.231 kb on - strand, within Rv1572c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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1,777,029 + Rv1569 0.28 -1.5
1,777,369 + Rv1569 0.57 -0.7
1,777,370 - Rv1569 0.58 -2.0
1,777,375 + Rv1569 0.58 -0.8
1,777,760 + -0.9
1,778,429 - Rv1570 0.84 -1.5
1,778,429 - Rv1570 0.84 -1.0
1,779,231 - Rv1572c 0.35 +1.2

Or see this region's nucleotide sequence