Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1569

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1568 and Rv1569 overlap by 4 nucleotidesRv1569 and Rv1570 overlap by 4 nucleotidesRv1570 and Rv1571 overlap by 1 nucleotides Rv1568: Rv1568 - Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA, at 1,775,392 to 1,776,705 Rv1568 Rv1569: Rv1569 - Probable 8-amino-7-oxononanoate synthase BioF1 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase), at 1,776,702 to 1,777,862 Rv1569 Rv1570: Rv1570 - Dethiobiotin synthetase BioD, at 1,777,859 to 1,778,539 Rv1570 Rv1571: Rv1571 - Conserved protein, at 1,778,539 to 1,779,048 Rv1571 Position (kb) 1776 1777 1778Strain fitness (log2 ratio) -2 -1 0 1at 1775.803 kb on + strand, within Rv1568at 1775.883 kb on + strand, within Rv1568at 1775.974 kb on + strand, within Rv1568at 1775.975 kb on - strand, within Rv1568at 1775.975 kb on - strand, within Rv1568at 1775.975 kb on - strand, within Rv1568at 1775.986 kb on + strand, within Rv1568at 1776.097 kb on + strand, within Rv1568at 1776.130 kb on + strand, within Rv1568at 1776.256 kb on + strand, within Rv1568at 1776.256 kb on + strand, within Rv1568at 1776.257 kb on - strand, within Rv1568at 1776.462 kb on + strand, within Rv1568at 1776.610 kb on + strandat 1776.625 kb on + strandat 1776.625 kb on + strandat 1776.626 kb on - strandat 1776.626 kb on - strandat 1776.626 kb on - strandat 1776.627 kb on + strandat 1776.627 kb on + strandat 1776.628 kb on - strandat 1776.628 kb on - strandat 1776.628 kb on - strandat 1776.689 kb on + strandat 1776.689 kb on + strandat 1776.689 kb on + strandat 1776.849 kb on + strand, within Rv1569at 1776.849 kb on + strand, within Rv1569at 1777.029 kb on + strand, within Rv1569at 1777.369 kb on + strand, within Rv1569at 1777.370 kb on - strand, within Rv1569at 1777.375 kb on + strand, within Rv1569at 1777.760 kb on + strandat 1778.429 kb on - strand, within Rv1570at 1778.429 kb on - strand, within Rv1570

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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1,775,803 + Rv1568 0.31 +1.6
1,775,883 + Rv1568 0.37 -0.6
1,775,974 + Rv1568 0.44 -1.3
1,775,975 - Rv1568 0.44 +0.6
1,775,975 - Rv1568 0.44 -1.1
1,775,975 - Rv1568 0.44 -0.8
1,775,986 + Rv1568 0.45 -1.0
1,776,097 + Rv1568 0.54 -0.7
1,776,130 + Rv1568 0.56 -1.1
1,776,256 + Rv1568 0.66 -0.7
1,776,256 + Rv1568 0.66 +0.3
1,776,257 - Rv1568 0.66 -0.1
1,776,462 + Rv1568 0.81 -0.3
1,776,610 + -0.8
1,776,625 + -0.8
1,776,625 + +1.6
1,776,626 - -0.4
1,776,626 - -0.0
1,776,626 - -1.0
1,776,627 + -1.1
1,776,627 + -1.4
1,776,628 - -1.0
1,776,628 - -0.4
1,776,628 - +0.6
1,776,689 + -0.9
1,776,689 + -0.4
1,776,689 + -1.0
1,776,849 + Rv1569 0.13 -1.0
1,776,849 + Rv1569 0.13 -1.6
1,777,029 + Rv1569 0.28 -1.5
1,777,369 + Rv1569 0.57 -0.7
1,777,370 - Rv1569 0.58 -2.0
1,777,375 + Rv1569 0.58 -0.8
1,777,760 + -0.9
1,778,429 - Rv1570 0.84 -1.5
1,778,429 - Rv1570 0.84 -1.0

Or see this region's nucleotide sequence