Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1414

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1412 and Rv1413 are separated by 213 nucleotidesRv1413 and Rv1414 overlap by 11 nucleotidesRv1414 and Rv1415 are separated by 104 nucleotides Rv1412: Rv1412 - Probable riboflavin synthase alpha chain RibC (RibE), at 1,588,567 to 1,589,172 Rv1412 Rv1413: Rv1413 - Conserved hypothetical protein, at 1,589,386 to 1,589,901 Rv1413 Rv1414: Rv1414 - Conserved hypothetical protein, at 1,589,891 to 1,590,292 Rv1414 Rv1415: Rv1415 - Probable riboflavin biosynthesis protein RibA2 : GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase), at 1,590,397 to 1,591,674 Rv1415 Position (kb) 1589 1590 1591Strain fitness (log2 ratio) -2 -1 0 1at 1589.226 kb on - strandat 1589.354 kb on + strandat 1589.354 kb on + strandat 1589.355 kb on - strandat 1589.411 kb on + strandat 1589.411 kb on + strandat 1589.438 kb on + strand, within Rv1413at 1589.439 kb on - strand, within Rv1413at 1589.439 kb on - strand, within Rv1413at 1589.439 kb on - strand, within Rv1413at 1589.439 kb on - strand, within Rv1413at 1589.439 kb on - strand, within Rv1413at 1589.449 kb on + strand, within Rv1413at 1589.449 kb on + strand, within Rv1413at 1589.450 kb on - strand, within Rv1413at 1589.450 kb on - strand, within Rv1413at 1589.888 kb on + strandat 1589.888 kb on + strandat 1589.889 kb on - strandat 1589.889 kb on - strandat 1590.216 kb on + strand, within Rv1414at 1590.317 kb on + strandat 1590.339 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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1,589,226 - -0.2
1,589,354 + -0.6
1,589,354 + +0.0
1,589,355 - -0.3
1,589,411 + -0.5
1,589,411 + -0.3
1,589,438 + Rv1413 0.10 -0.3
1,589,439 - Rv1413 0.10 -0.1
1,589,439 - Rv1413 0.10 +0.9
1,589,439 - Rv1413 0.10 -1.9
1,589,439 - Rv1413 0.10 -1.8
1,589,439 - Rv1413 0.10 -0.4
1,589,449 + Rv1413 0.12 +0.0
1,589,449 + Rv1413 0.12 -0.8
1,589,450 - Rv1413 0.12 -0.9
1,589,450 - Rv1413 0.12 -0.9
1,589,888 + +0.2
1,589,888 + -0.9
1,589,889 - -0.9
1,589,889 - -0.2
1,590,216 + Rv1414 0.81 -0.6
1,590,317 + +0.3
1,590,339 + -0.8

Or see this region's nucleotide sequence