Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1351

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1349 and Rv1350 are separated by 128 nucleotidesRv1350 and Rv1351 overlap by 4 nucleotidesRv1351 and Rv1352 are separated by 202 nucleotidesRv1352 and Rv1353c are separated by 65 nucleotides Rv1349: Rv1349 - Iron-regulated transporter IrtB, at 1,515,623 to 1,517,362 Rv1349 Rv1350: Rv1350 - Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase), at 1,517,491 to 1,518,234 Rv1350 Rv1351: Rv1351 - Hypothetical protein, at 1,518,231 to 1,518,560 Rv1351 Rv1352: Rv1352 - Conserved protein, at 1,518,763 to 1,519,134 Rv1352 Rv1353c: Rv1353c - Probable transcriptional regulatory protein, at 1,519,200 to 1,519,985 Rv1353c Position (kb) 1518 1519Strain fitness (log2 ratio) -3 -2 -1 0 1at 1517.480 kb on - strandat 1517.553 kb on - strandat 1517.954 kb on - strand, within Rv1350at 1517.979 kb on - strand, within Rv1350at 1518.188 kb on - strandat 1518.230 kb on + strandat 1518.230 kb on + strandat 1518.349 kb on + strand, within Rv1351at 1518.459 kb on + strand, within Rv1351at 1518.542 kb on + strandat 1518.714 kb on + strandat 1518.714 kb on + strandat 1518.750 kb on + strandat 1518.751 kb on - strandat 1518.751 kb on - strandat 1518.751 kb on - strandat 1518.919 kb on + strand, within Rv1352at 1518.948 kb on + strand, within Rv1352at 1519.050 kb on + strand, within Rv1352at 1519.050 kb on + strand, within Rv1352at 1519.342 kb on + strand, within Rv1353cat 1519.535 kb on - strand, within Rv1353c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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1,517,480 - +0.4
1,517,553 - -0.1
1,517,954 - Rv1350 0.62 -0.5
1,517,979 - Rv1350 0.66 +0.1
1,518,188 - -1.0
1,518,230 + -1.0
1,518,230 + +0.4
1,518,349 + Rv1351 0.36 -0.2
1,518,459 + Rv1351 0.69 -2.8
1,518,542 + +0.5
1,518,714 + -0.8
1,518,714 + -0.2
1,518,750 + +0.2
1,518,751 - +0.1
1,518,751 - -0.0
1,518,751 - -1.0
1,518,919 + Rv1352 0.42 -0.0
1,518,948 + Rv1352 0.50 -0.3
1,519,050 + Rv1352 0.77 -0.4
1,519,050 + Rv1352 0.77 -0.2
1,519,342 + Rv1353c 0.18 -0.2
1,519,535 - Rv1353c 0.43 -0.9

Or see this region's nucleotide sequence