Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1013

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1011 and Rv1012 are separated by 16 nucleotidesRv1012 and Rv1013 are separated by 203 nucleotidesRv1013 and Rv1014c are separated by 73 nucleotidesRv1014c and Rv1015c are separated by 12 nucleotides Rv1011: Rv1011 - Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase), at 1,130,191 to 1,131,111 Rv1011 Rv1012: Rv1012 - Hypothetical protein, at 1,131,128 to 1,131,421 Rv1012 Rv1013: Rv1013 - Putative polyketide synthase Pks16, at 1,131,625 to 1,133,259 Rv1013 Rv1014c: Rv1014c - Probable peptidyl-tRNA hydrolase Pth, at 1,133,333 to 1,133,908 Rv1014c Rv1015c: Rv1015c - 50S ribosomal protein L25 RplY, at 1,133,921 to 1,134,568 Rv1015c Position (kb) 1131 1132 1133 1134Strain fitness (log2 ratio) -2 -1 0 1at 1131.269 kb on + strand, within Rv1012at 1131.270 kb on - strand, within Rv1012at 1131.328 kb on + strand, within Rv1012at 1131.460 kb on - strandat 1131.460 kb on - strandat 1132.024 kb on - strand, within Rv1013at 1132.024 kb on - strand, within Rv1013at 1132.024 kb on - strand, within Rv1013at 1132.156 kb on + strand, within Rv1013at 1132.157 kb on - strand, within Rv1013at 1132.192 kb on + strand, within Rv1013at 1132.192 kb on + strand, within Rv1013at 1132.357 kb on + strand, within Rv1013at 1132.357 kb on + strand, within Rv1013at 1132.358 kb on - strand, within Rv1013at 1132.358 kb on - strand, within Rv1013at 1132.709 kb on + strand, within Rv1013at 1132.731 kb on - strand, within Rv1013at 1132.823 kb on - strand, within Rv1013at 1132.830 kb on + strand, within Rv1013at 1132.830 kb on + strand, within Rv1013at 1132.871 kb on - strand, within Rv1013at 1132.920 kb on - strand, within Rv1013at 1132.962 kb on + strand, within Rv1013at 1132.963 kb on - strand, within Rv1013at 1133.258 kb on - strandat 1133.335 kb on - strandat 1133.961 kb on - strandat 1133.961 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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1,131,269 + Rv1012 0.48 -0.3
1,131,270 - Rv1012 0.48 -0.3
1,131,328 + Rv1012 0.68 -0.4
1,131,460 - +0.6
1,131,460 - +0.1
1,132,024 - Rv1013 0.24 -1.1
1,132,024 - Rv1013 0.24 -1.0
1,132,024 - Rv1013 0.24 -1.2
1,132,156 + Rv1013 0.32 -0.8
1,132,157 - Rv1013 0.33 -1.0
1,132,192 + Rv1013 0.35 -1.3
1,132,192 + Rv1013 0.35 -0.2
1,132,357 + Rv1013 0.45 -2.0
1,132,357 + Rv1013 0.45 -1.1
1,132,358 - Rv1013 0.45 -1.3
1,132,358 - Rv1013 0.45 -0.8
1,132,709 + Rv1013 0.66 -1.1
1,132,731 - Rv1013 0.68 -2.5
1,132,823 - Rv1013 0.73 +0.4
1,132,830 + Rv1013 0.74 -1.2
1,132,830 + Rv1013 0.74 -1.6
1,132,871 - Rv1013 0.76 -1.3
1,132,920 - Rv1013 0.79 -0.2
1,132,962 + Rv1013 0.82 -0.4
1,132,963 - Rv1013 0.82 -1.4
1,133,258 - -0.1
1,133,335 - +0.3
1,133,961 - +0.3
1,133,961 - +0.8

Or see this region's nucleotide sequence