Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0435c

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0433 and Rv0434 are separated by 59 nucleotidesRv0434 and Rv0435c are separated by 179 nucleotidesRv0435c and Rv0436c overlap by 4 nucleotidesRv0436c and Rv0437c overlap by 4 nucleotides Rv0433: Rv0433 - Conserved hypothetical protein, at 520,324 to 521,454 Rv0433 Rv0434: Rv0434 - Conserved hypothetical protein, at 521,514 to 522,167 Rv0434 Rv0435c: Rv0435c - Putative conserved ATPase, at 522,347 to 524,533 Rv0435c Rv0436c: Rv0436c - Probable CDP-diacylglycerol--serine O-phosphatidyltransferase PssA (PS synthase) (phosphatidylserine synthase), at 524,530 to 525,390 Rv0436c Rv0437c: Rv0437c - Possible phosphatidylserine decarboxylase Psd (PS decarboxylase), at 525,387 to 526,082 Rv0437c Position (kb) 522 523 524 525Strain fitness (log2 ratio) -2 -1 0 1 2at 521.508 kb on + strandat 521.509 kb on - strandat 521.509 kb on - strandat 521.509 kb on - strandat 521.611 kb on - strand, within Rv0434at 521.665 kb on + strand, within Rv0434at 521.665 kb on + strand, within Rv0434at 521.666 kb on - strand, within Rv0434at 521.666 kb on - strand, within Rv0434at 521.666 kb on - strand, within Rv0434at 521.767 kb on - strand, within Rv0434at 521.767 kb on - strand, within Rv0434at 521.768 kb on + strand, within Rv0434at 521.768 kb on + strand, within Rv0434at 521.768 kb on + strand, within Rv0434at 521.769 kb on - strand, within Rv0434at 521.846 kb on - strand, within Rv0434at 522.165 kb on + strandat 522.166 kb on - strandat 522.229 kb on + strandat 522.230 kb on - strandat 522.230 kb on - strandat 522.231 kb on + strandat 522.231 kb on + strandat 522.231 kb on + strandat 522.231 kb on + strandat 522.231 kb on + strandat 522.232 kb on - strandat 522.232 kb on - strandat 522.379 kb on + strandat 522.533 kb on - strandat 522.533 kb on - strandat 522.693 kb on - strand, within Rv0435cat 522.719 kb on + strand, within Rv0435cat 522.719 kb on + strand, within Rv0435cat 522.720 kb on - strand, within Rv0435cat 522.748 kb on + strand, within Rv0435cat 522.748 kb on + strand, within Rv0435cat 522.887 kb on + strand, within Rv0435cat 523.056 kb on - strand, within Rv0435cat 523.512 kb on - strand, within Rv0435cat 523.817 kb on + strand, within Rv0435cat 523.817 kb on + strand, within Rv0435cat 523.817 kb on + strand, within Rv0435cat 523.820 kb on + strand, within Rv0435cat 524.115 kb on - strand, within Rv0435cat 524.247 kb on + strand, within Rv0435cat 524.248 kb on - strand, within Rv0435cat 524.932 kb on + strand, within Rv0436cat 524.932 kb on + strand, within Rv0436cat 524.933 kb on - strand, within Rv0436cat 525.032 kb on + strand, within Rv0436cat 525.116 kb on + strand, within Rv0436cat 525.347 kb on - strandat 525.359 kb on - strandat 525.359 kb on - strandat 525.470 kb on - strand, within Rv0437cat 525.506 kb on - strand, within Rv0437c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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521,508 + +0.9
521,509 - +0.5
521,509 - +0.1
521,509 - -0.2
521,611 - Rv0434 0.15 +1.6
521,665 + Rv0434 0.23 -0.1
521,665 + Rv0434 0.23 -2.2
521,666 - Rv0434 0.23 +0.0
521,666 - Rv0434 0.23 -0.7
521,666 - Rv0434 0.23 -0.2
521,767 - Rv0434 0.39 +0.6
521,767 - Rv0434 0.39 -1.9
521,768 + Rv0434 0.39 +0.6
521,768 + Rv0434 0.39 -0.3
521,768 + Rv0434 0.39 +1.3
521,769 - Rv0434 0.39 -0.3
521,846 - Rv0434 0.51 -1.3
522,165 + +0.6
522,166 - -0.2
522,229 + +0.3
522,230 - +1.9
522,230 - -0.2
522,231 + -0.1
522,231 + +0.0
522,231 + +0.3
522,231 + -0.5
522,231 + -0.6
522,232 - +0.1
522,232 - -0.6
522,379 + -0.5
522,533 - -0.1
522,533 - +0.4
522,693 - Rv0435c 0.16 -0.5
522,719 + Rv0435c 0.17 +0.1
522,719 + Rv0435c 0.17 +0.6
522,720 - Rv0435c 0.17 -0.2
522,748 + Rv0435c 0.18 -1.4
522,748 + Rv0435c 0.18 +1.6
522,887 + Rv0435c 0.25 -0.4
523,056 - Rv0435c 0.32 -0.5
523,512 - Rv0435c 0.53 -0.4
523,817 + Rv0435c 0.67 -0.6
523,817 + Rv0435c 0.67 -0.0
523,817 + Rv0435c 0.67 -0.4
523,820 + Rv0435c 0.67 +0.6
524,115 - Rv0435c 0.81 +1.6
524,247 + Rv0435c 0.87 +0.6
524,248 - Rv0435c 0.87 -0.1
524,932 + Rv0436c 0.47 -1.6
524,932 + Rv0436c 0.47 -1.8
524,933 - Rv0436c 0.47 -2.1
525,032 + Rv0436c 0.58 -1.4
525,116 + Rv0436c 0.68 +0.6
525,347 - -0.9
525,359 - -1.3
525,359 - +2.6
525,470 - Rv0437c 0.12 -0.9
525,506 - Rv0437c 0.17 +0.7

Or see this region's nucleotide sequence