Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0012

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0010c and Rv0011c are separated by 155 nucleotidesRv0011c and Rv0012 are separated by 93 nucleotidesRv0012 and Rv0013 are separated by 36 nucleotidesRv0013 and Rv0014c overlap by 23 nucleotides Rv0010c: Rv0010c - Probable conserved membrane protein, at 13,133 to 13,558 Rv0010c Rv0011c: Rv0011c - Probable conserved transmembrane protein, at 13,714 to 13,995 Rv0011c Rv0012: Rv0012 - Probable conserved membrane protein, at 14,089 to 14,877 Rv0012 Rv0013: Rv0013 - Possible anthranilate synthase component II TrpG (glutamine amidotransferase), at 14,914 to 15,612 Rv0013 Rv0014c: Rv0014c - Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B), at 15,590 to 17,470 Rv0014c Position (kb) 14 15Strain fitness (log2 ratio) -2 -1 0 1 2at 13.156 kb on - strandat 13.309 kb on + strand, within Rv0010cat 13.309 kb on + strand, within Rv0010cat 13.323 kb on - strand, within Rv0010cat 13.323 kb on - strand, within Rv0010cat 13.325 kb on + strand, within Rv0010cat 13.326 kb on - strand, within Rv0010cat 13.369 kb on + strand, within Rv0010cat 13.568 kb on - strandat 14.059 kb on + strandat 14.059 kb on + strandat 14.089 kb on - strandat 14.097 kb on - strandat 14.097 kb on - strandat 14.622 kb on - strand, within Rv0012at 14.661 kb on + strand, within Rv0012at 14.662 kb on - strand, within Rv0012at 14.662 kb on - strand, within Rv0012at 14.665 kb on + strand, within Rv0012at 14.666 kb on - strand, within Rv0012at 14.666 kb on - strand, within Rv0012at 14.666 kb on - strand, within Rv0012at 14.750 kb on - strand, within Rv0012at 14.750 kb on - strand, within Rv0012at 14.758 kb on + strand, within Rv0012at 14.758 kb on + strand, within Rv0012at 14.813 kb on + strandat 15.591 kb on + strandat 15.592 kb on - strandat 15.592 kb on - strandat 15.592 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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13,156 - -0.3
13,309 + Rv0010c 0.41 -0.5
13,309 + Rv0010c 0.41 +2.1
13,323 - Rv0010c 0.45 -0.3
13,323 - Rv0010c 0.45 +0.1
13,325 + Rv0010c 0.45 +1.2
13,326 - Rv0010c 0.45 -0.4
13,369 + Rv0010c 0.55 -0.7
13,568 - +0.4
14,059 + -0.1
14,059 + -0.3
14,089 - -0.2
14,097 - +0.0
14,097 - -0.6
14,622 - Rv0012 0.68 -1.4
14,661 + Rv0012 0.72 -1.2
14,662 - Rv0012 0.73 -2.3
14,662 - Rv0012 0.73 -1.1
14,665 + Rv0012 0.73 -0.8
14,666 - Rv0012 0.73 -0.9
14,666 - Rv0012 0.73 -1.8
14,666 - Rv0012 0.73 -0.7
14,750 - Rv0012 0.84 -2.1
14,750 - Rv0012 0.84 -2.3
14,758 + Rv0012 0.85 -0.3
14,758 + Rv0012 0.85 -1.8
14,813 + +0.5
15,591 + -0.5
15,592 - -0.1
15,592 - -0.6
15,592 - +0.4

Or see this region's nucleotide sequence