Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3495c

Experiment: L-Asparagine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3494c and Rv3495c are separated by 10 nucleotidesRv3495c and Rv3496c overlap by 4 nucleotides Rv3494c: Rv3494c - Mce-family protein Mce4F, at 3,911,675 to 3,913,369 Rv3494c Rv3495c: Rv3495c - Possible Mce-family lipoprotein LprN (Mce-family lipoprotein Mce4E), at 3,913,380 to 3,914,534 Rv3495c Rv3496c: Rv3496c - Mce-family protein Mce4D, at 3,914,531 to 3,915,886 Rv3496c Position (kb) 3913 3914 3915Strain fitness (log2 ratio) -2 -1 0 1at 3912.452 kb on + strand, within Rv3494cat 3912.528 kb on + strand, within Rv3494cat 3912.789 kb on + strand, within Rv3494cat 3912.790 kb on - strand, within Rv3494cat 3913.037 kb on + strand, within Rv3494cat 3913.038 kb on - strand, within Rv3494cat 3913.038 kb on - strand, within Rv3494cat 3913.048 kb on - strand, within Rv3494cat 3913.076 kb on + strand, within Rv3494cat 3913.076 kb on + strand, within Rv3494cat 3913.212 kb on + strandat 3913.213 kb on - strandat 3913.251 kb on + strandat 3913.288 kb on - strandat 3913.413 kb on - strandat 3913.513 kb on + strand, within Rv3495cat 3913.514 kb on - strand, within Rv3495cat 3913.577 kb on + strand, within Rv3495cat 3913.577 kb on + strand, within Rv3495cat 3913.578 kb on - strand, within Rv3495cat 3913.578 kb on - strand, within Rv3495cat 3913.578 kb on - strand, within Rv3495cat 3913.583 kb on - strand, within Rv3495cat 3913.583 kb on - strand, within Rv3495cat 3913.696 kb on + strand, within Rv3495cat 3914.051 kb on + strand, within Rv3495cat 3914.188 kb on - strand, within Rv3495cat 3914.193 kb on + strand, within Rv3495cat 3914.193 kb on + strand, within Rv3495cat 3914.193 kb on + strand, within Rv3495cat 3914.194 kb on - strand, within Rv3495cat 3914.194 kb on - strand, within Rv3495cat 3914.612 kb on + strandat 3914.612 kb on + strandat 3914.613 kb on - strandat 3914.613 kb on - strandat 3914.613 kb on - strandat 3914.721 kb on + strand, within Rv3496cat 3914.722 kb on - strand, within Rv3496cat 3914.722 kb on - strand, within Rv3496cat 3914.782 kb on - strand, within Rv3496cat 3914.964 kb on + strand, within Rv3496cat 3914.964 kb on + strand, within Rv3496cat 3914.964 kb on + strand, within Rv3496cat 3914.964 kb on + strand, within Rv3496cat 3914.965 kb on - strand, within Rv3496cat 3914.965 kb on - strand, within Rv3496cat 3914.966 kb on + strand, within Rv3496cat 3914.973 kb on + strand, within Rv3496cat 3914.973 kb on + strand, within Rv3496cat 3914.973 kb on + strand, within Rv3496cat 3915.255 kb on - strand, within Rv3496cat 3915.527 kb on + strand, within Rv3496c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Asparagine (C)
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3,912,452 + Rv3494c 0.46 +0.7
3,912,528 + Rv3494c 0.50 +1.7
3,912,789 + Rv3494c 0.66 -0.8
3,912,790 - Rv3494c 0.66 -1.6
3,913,037 + Rv3494c 0.80 -0.9
3,913,038 - Rv3494c 0.80 -0.3
3,913,038 - Rv3494c 0.80 -1.0
3,913,048 - Rv3494c 0.81 +0.0
3,913,076 + Rv3494c 0.83 -1.7
3,913,076 + Rv3494c 0.83 +0.7
3,913,212 + -0.5
3,913,213 - -0.7
3,913,251 + -1.5
3,913,288 - -1.1
3,913,413 - +1.7
3,913,513 + Rv3495c 0.12 -0.1
3,913,514 - Rv3495c 0.12 -1.6
3,913,577 + Rv3495c 0.17 -0.8
3,913,577 + Rv3495c 0.17 -0.6
3,913,578 - Rv3495c 0.17 -0.7
3,913,578 - Rv3495c 0.17 -0.5
3,913,578 - Rv3495c 0.17 -0.8
3,913,583 - Rv3495c 0.18 +0.1
3,913,583 - Rv3495c 0.18 -0.6
3,913,696 + Rv3495c 0.27 -1.2
3,914,051 + Rv3495c 0.58 -0.1
3,914,188 - Rv3495c 0.70 -0.2
3,914,193 + Rv3495c 0.70 -0.6
3,914,193 + Rv3495c 0.70 -0.9
3,914,193 + Rv3495c 0.70 -0.8
3,914,194 - Rv3495c 0.70 -1.1
3,914,194 - Rv3495c 0.70 -0.9
3,914,612 + -0.2
3,914,612 + -1.1
3,914,613 - +0.1
3,914,613 - -0.1
3,914,613 - +0.0
3,914,721 + Rv3496c 0.14 -0.7
3,914,722 - Rv3496c 0.14 -1.3
3,914,722 - Rv3496c 0.14 -1.5
3,914,782 - Rv3496c 0.19 -0.6
3,914,964 + Rv3496c 0.32 -0.6
3,914,964 + Rv3496c 0.32 -0.3
3,914,964 + Rv3496c 0.32 -0.6
3,914,964 + Rv3496c 0.32 -1.0
3,914,965 - Rv3496c 0.32 -0.7
3,914,965 - Rv3496c 0.32 -2.1
3,914,966 + Rv3496c 0.32 -0.6
3,914,973 + Rv3496c 0.33 -0.6
3,914,973 + Rv3496c 0.33 -0.7
3,914,973 + Rv3496c 0.33 -0.8
3,915,255 - Rv3496c 0.53 -1.0
3,915,527 + Rv3496c 0.73 -1.1

Or see this region's nucleotide sequence