Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1220c

Experiment: L-Asparagine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1218c and Rv1219c overlap by 11 nucleotidesRv1219c and Rv1220c are separated by 141 nucleotidesRv1220c and Rv1221 are separated by 262 nucleotides Rv1218c: Rv1218c - Probable tetronasin-transport ATP-binding protein ABC transporter, at 1,361,798 to 1,362,733 Rv1218c Rv1219c: Rv1219c - Probable transcriptional regulatory protein, at 1,362,723 to 1,363,361 Rv1219c Rv1220c: Rv1220c - Probable methyltransferase, at 1,363,503 to 1,364,150 Rv1220c Rv1221: Rv1221 - Alternative RNA polymerase sigma factor SigE, at 1,364,413 to 1,365,186 Rv1221 Position (kb) 1363 1364 1365Strain fitness (log2 ratio) -3 -2 -1 0 1at 1362.567 kb on - strand, within Rv1218cat 1362.772 kb on + strandat 1362.772 kb on + strandat 1362.773 kb on - strandat 1362.773 kb on - strandat 1362.805 kb on + strand, within Rv1219cat 1362.806 kb on - strand, within Rv1219cat 1362.842 kb on - strand, within Rv1219cat 1362.978 kb on + strand, within Rv1219cat 1363.072 kb on + strand, within Rv1219cat 1363.073 kb on - strand, within Rv1219cat 1363.073 kb on - strand, within Rv1219cat 1363.073 kb on - strand, within Rv1219cat 1363.090 kb on + strand, within Rv1219cat 1363.091 kb on - strand, within Rv1219cat 1363.380 kb on - strandat 1363.505 kb on - strandat 1363.711 kb on + strand, within Rv1220cat 1363.711 kb on + strand, within Rv1220cat 1363.712 kb on - strand, within Rv1220cat 1363.712 kb on - strand, within Rv1220cat 1363.747 kb on - strand, within Rv1220cat 1363.757 kb on - strand, within Rv1220cat 1363.863 kb on + strand, within Rv1220cat 1363.864 kb on - strand, within Rv1220cat 1363.864 kb on - strand, within Rv1220cat 1363.864 kb on - strand, within Rv1220cat 1363.864 kb on - strand, within Rv1220cat 1364.088 kb on + strandat 1364.088 kb on + strandat 1364.188 kb on + strandat 1364.188 kb on + strandat 1364.353 kb on + strandat 1364.376 kb on + strandat 1364.376 kb on + strandat 1364.376 kb on + strandat 1364.376 kb on + strandat 1364.376 kb on + strandat 1364.376 kb on + strandat 1364.376 kb on + strandat 1364.378 kb on + strandat 1364.378 kb on + strandat 1364.378 kb on + strandat 1364.379 kb on - strandat 1364.379 kb on - strandat 1364.387 kb on + strandat 1364.405 kb on + strandat 1364.445 kb on + strandat 1364.491 kb on + strand, within Rv1221at 1364.491 kb on + strand, within Rv1221at 1364.520 kb on + strand, within Rv1221at 1364.520 kb on + strand, within Rv1221

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Asparagine (C)
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1,362,567 - Rv1218c 0.82 -0.1
1,362,772 + -0.5
1,362,772 + +0.3
1,362,773 - -2.1
1,362,773 - -0.4
1,362,805 + Rv1219c 0.13 -0.1
1,362,806 - Rv1219c 0.13 -0.9
1,362,842 - Rv1219c 0.19 -0.4
1,362,978 + Rv1219c 0.40 +0.0
1,363,072 + Rv1219c 0.55 -0.3
1,363,073 - Rv1219c 0.55 +0.2
1,363,073 - Rv1219c 0.55 -0.4
1,363,073 - Rv1219c 0.55 -1.2
1,363,090 + Rv1219c 0.57 -0.2
1,363,091 - Rv1219c 0.58 +0.0
1,363,380 - -0.2
1,363,505 - -0.3
1,363,711 + Rv1220c 0.32 -0.1
1,363,711 + Rv1220c 0.32 -1.1
1,363,712 - Rv1220c 0.32 -0.8
1,363,712 - Rv1220c 0.32 -0.0
1,363,747 - Rv1220c 0.38 -1.1
1,363,757 - Rv1220c 0.39 -0.1
1,363,863 + Rv1220c 0.56 -1.2
1,363,864 - Rv1220c 0.56 -0.6
1,363,864 - Rv1220c 0.56 -0.5
1,363,864 - Rv1220c 0.56 -0.6
1,363,864 - Rv1220c 0.56 +0.2
1,364,088 + -0.8
1,364,088 + -0.3
1,364,188 + -0.2
1,364,188 + -0.2
1,364,353 + -0.5
1,364,376 + +1.6
1,364,376 + -1.6
1,364,376 + +0.2
1,364,376 + -0.5
1,364,376 + -0.5
1,364,376 + -0.9
1,364,376 + -0.1
1,364,378 + -3.5
1,364,378 + -0.4
1,364,378 + +0.2
1,364,379 - +0.5
1,364,379 - -1.9
1,364,387 + -0.9
1,364,405 + -0.9
1,364,445 + -0.4
1,364,491 + Rv1221 0.10 +0.0
1,364,491 + Rv1221 0.10 -0.3
1,364,520 + Rv1221 0.14 -0.3
1,364,520 + Rv1221 0.14 -0.7

Or see this region's nucleotide sequence