Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2505c

Experiment: L-Asparagine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2503c and Rv2504c overlap by 4 nucleotidesRv2504c and Rv2505c are separated by 82 nucleotidesRv2505c and Rv2506 are separated by 115 nucleotidesRv2506 and Rv2507 are separated by 78 nucleotides Rv2503c: Rv2503c - Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (beta subunit) ScoB (3-oxo-acid:CoA transferase) (OXCT B) (succinyl CoA:3-oxoacid CoA-transferase), at 2,818,471 to 2,819,127 Rv2503c Rv2504c: Rv2504c - Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (alpha subunit) ScoA (3-oxo acid:CoA transferase) (OXCT A) (succinyl-CoA:3-oxoacid-coenzyme A transferase), at 2,819,124 to 2,819,870 Rv2504c Rv2505c: Rv2505c - Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 2,819,953 to 2,821,596 Rv2505c Rv2506: Rv2506 - Probable transcriptional regulatory protein (probably TetR-family), at 2,821,712 to 2,822,359 Rv2506 Rv2507: Rv2507 - Possible conserved proline rich membrane protein, at 2,822,438 to 2,823,259 Rv2507 Position (kb) 2819 2820 2821 2822Strain fitness (log2 ratio) -1 0 1 2 3at 2819.057 kb on + strand, within Rv2503cat 2819.058 kb on - strand, within Rv2503cat 2819.208 kb on + strand, within Rv2504cat 2819.318 kb on - strand, within Rv2504cat 2819.395 kb on + strand, within Rv2504cat 2819.396 kb on - strand, within Rv2504cat 2819.518 kb on + strand, within Rv2504cat 2819.519 kb on - strand, within Rv2504cat 2819.827 kb on - strandat 2819.923 kb on - strandat 2819.946 kb on - strandat 2819.946 kb on - strandat 2820.008 kb on - strandat 2820.092 kb on + strandat 2820.092 kb on + strandat 2820.207 kb on + strand, within Rv2505cat 2820.207 kb on + strand, within Rv2505cat 2820.396 kb on - strand, within Rv2505cat 2820.588 kb on - strand, within Rv2505cat 2820.695 kb on + strand, within Rv2505cat 2820.749 kb on + strand, within Rv2505cat 2820.862 kb on + strand, within Rv2505cat 2820.881 kb on + strand, within Rv2505cat 2820.920 kb on + strand, within Rv2505cat 2820.945 kb on - strand, within Rv2505cat 2821.014 kb on - strand, within Rv2505cat 2821.179 kb on - strand, within Rv2505cat 2821.242 kb on - strand, within Rv2505cat 2821.282 kb on + strand, within Rv2505cat 2821.430 kb on + strand, within Rv2505cat 2821.557 kb on - strandat 2821.557 kb on - strandat 2821.616 kb on + strandat 2821.647 kb on + strandat 2821.648 kb on - strandat 2821.648 kb on - strandat 2821.658 kb on - strandat 2821.672 kb on + strandat 2821.898 kb on + strand, within Rv2506at 2822.091 kb on + strand, within Rv2506at 2822.144 kb on + strand, within Rv2506at 2822.255 kb on - strand, within Rv2506at 2822.255 kb on - strand, within Rv2506at 2822.355 kb on + strandat 2822.356 kb on - strandat 2822.356 kb on - strandat 2822.356 kb on - strandat 2822.357 kb on + strandat 2822.357 kb on + strandat 2822.358 kb on - strandat 2822.358 kb on - strandat 2822.415 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Asparagine (C)
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2,819,057 + Rv2503c 0.89 -0.3
2,819,058 - Rv2503c 0.89 +1.6
2,819,208 + Rv2504c 0.11 -0.5
2,819,318 - Rv2504c 0.26 -0.8
2,819,395 + Rv2504c 0.36 +2.9
2,819,396 - Rv2504c 0.36 -0.8
2,819,518 + Rv2504c 0.53 -0.8
2,819,519 - Rv2504c 0.53 -0.1
2,819,827 - -0.4
2,819,923 - +1.0
2,819,946 - +0.5
2,819,946 - +0.4
2,820,008 - -0.0
2,820,092 + +0.6
2,820,092 + +0.3
2,820,207 + Rv2505c 0.15 +1.6
2,820,207 + Rv2505c 0.15 +1.6
2,820,396 - Rv2505c 0.27 -0.2
2,820,588 - Rv2505c 0.39 +0.6
2,820,695 + Rv2505c 0.45 +0.6
2,820,749 + Rv2505c 0.48 +0.2
2,820,862 + Rv2505c 0.55 +0.5
2,820,881 + Rv2505c 0.56 -0.9
2,820,920 + Rv2505c 0.59 -0.2
2,820,945 - Rv2505c 0.60 +0.9
2,821,014 - Rv2505c 0.65 +0.5
2,821,179 - Rv2505c 0.75 +0.9
2,821,242 - Rv2505c 0.78 -0.2
2,821,282 + Rv2505c 0.81 -0.0
2,821,430 + Rv2505c 0.90 -0.6
2,821,557 - -0.2
2,821,557 - +0.1
2,821,616 + -1.4
2,821,647 + +0.4
2,821,648 - +0.6
2,821,648 - +0.6
2,821,658 - +1.2
2,821,672 + +0.8
2,821,898 + Rv2506 0.29 +1.8
2,822,091 + Rv2506 0.58 +1.6
2,822,144 + Rv2506 0.67 +1.3
2,822,255 - Rv2506 0.84 +1.3
2,822,255 - Rv2506 0.84 +0.1
2,822,355 + +0.3
2,822,356 - -1.4
2,822,356 - +0.7
2,822,356 - +1.5
2,822,357 + +1.0
2,822,357 + -0.2
2,822,358 - +0.4
2,822,358 - -0.1
2,822,415 - -0.2

Or see this region's nucleotide sequence