Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2495c

Experiment: L-Asparagine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2492 and Rv2493 are separated by 52 nucleotidesRv2493 and Rv2494 are separated by 5 nucleotidesRv2494 and Rv2495c are separated by 22 nucleotidesRv2495c and Rv2496c overlap by 4 nucleotides Rv2492: Rv2492 - Hypothetical protein, at 2,807,278 to 2,808,030 Rv2492 Rv2493: Rv2493 - Possible antitoxin VapB38, at 2,808,083 to 2,808,304 Rv2493 Rv2494: Rv2494 - Possible toxin VapC38. Contains PIN domain., at 2,808,310 to 2,808,735 Rv2494 Rv2495c: Rv2495c - Probable branched-chain keto acid dehydrogenase E2 component BkdC, at 2,808,758 to 2,809,939 Rv2495c Rv2496c: Rv2496c - Probable branched-chain keto acid dehydrogenase E1 component, beta subunit BkdB, at 2,809,936 to 2,810,982 Rv2496c Position (kb) 2808 2809 2810Strain fitness (log2 ratio) -2 -1 0 1at 2807.944 kb on - strand, within Rv2492at 2808.029 kb on - strandat 2808.040 kb on + strandat 2810.253 kb on + strand, within Rv2496cat 2810.408 kb on + strand, within Rv2496cat 2810.510 kb on + strand, within Rv2496cat 2810.510 kb on + strand, within Rv2496cat 2810.550 kb on + strand, within Rv2496cat 2810.701 kb on + strand, within Rv2496cat 2810.701 kb on + strand, within Rv2496cat 2810.779 kb on - strand, within Rv2496cat 2810.874 kb on - strand, within Rv2496c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Asparagine (C)
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2,807,944 - Rv2492 0.88 -1.1
2,808,029 - -0.3
2,808,040 + +0.1
2,810,253 + Rv2496c 0.30 -0.7
2,810,408 + Rv2496c 0.45 -2.2
2,810,510 + Rv2496c 0.55 -2.0
2,810,510 + Rv2496c 0.55 +1.6
2,810,550 + Rv2496c 0.59 -1.7
2,810,701 + Rv2496c 0.73 -1.0
2,810,701 + Rv2496c 0.73 -0.0
2,810,779 - Rv2496c 0.81 -1.0
2,810,874 - Rv2496c 0.90 -0.6

Or see this region's nucleotide sequence