Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1853

Experiment: L-Asparagine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1851 and Rv1852 are separated by 10 nucleotidesRv1852 and Rv1853 are separated by 7 nucleotidesRv1853 and Rv1854c are separated by 2 nucleotides Rv1851: Rv1851 - Urease accessory protein UreF, at 2,099,694 to 2,100,329 Rv1851 Rv1852: Rv1852 - Urease accessory protein UreG, at 2,100,340 to 2,101,014 Rv1852 Rv1853: Rv1853 - Probable urease accessory protein UreD, at 2,101,022 to 2,101,648 Rv1853 Rv1854c: Rv1854c - Probable NADH dehydrogenase Ndh, at 2,101,651 to 2,103,042 Rv1854c Position (kb) 2101 2102Strain fitness (log2 ratio) -1 0 1at 2100.120 kb on + strand, within Rv1851at 2100.169 kb on + strand, within Rv1851at 2100.526 kb on + strand, within Rv1852at 2101.013 kb on - strandat 2101.526 kb on - strand, within Rv1853at 2101.619 kb on - strandat 2101.652 kb on + strandat 2101.665 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Asparagine (C)
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2,100,120 + Rv1851 0.67 +0.4
2,100,169 + Rv1851 0.75 +0.8
2,100,526 + Rv1852 0.28 -0.2
2,101,013 - -0.2
2,101,526 - Rv1853 0.80 -0.1
2,101,619 - +0.3
2,101,652 + +0.7
2,101,665 + -0.9

Or see this region's nucleotide sequence