Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2594c

Experiment: pyruvate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2592c and Rv2593c overlap by 4 nucleotidesRv2593c and Rv2594c overlap by 4 nucleotidesRv2594c and Rv2595 are separated by 108 nucleotidesRv2595 and Rv2596 overlap by 4 nucleotidesRv2596 and Rv2597 are separated by 216 nucleotides Rv2592c: Rv2592c - Probable holliday junction DNA helicase RuvB, at 2,923,199 to 2,924,233 Rv2592c Rv2593c: Rv2593c - Probable holliday junction DNA helicase RuvA, at 2,924,230 to 2,924,820 Rv2593c Rv2594c: Rv2594c - Probable crossover junction endodeoxyribonuclease RuvC (holliday junction nuclease) (holliday junction resolvase), at 2,924,817 to 2,925,383 Rv2594c Rv2595: Rv2595 - Possible antitoxin VapB40, at 2,925,492 to 2,925,737 Rv2595 Rv2596: Rv2596 - Possible toxin VapC40. Contains PIN domain., at 2,925,734 to 2,926,138 Rv2596 Rv2597: Rv2597 - Probable membrane protein, at 2,926,355 to 2,926,975 Rv2597 Position (kb) 2924 2925 2926Strain fitness (log2 ratio) -1 0 1at 2925.462 kb on + strandat 2925.463 kb on - strandat 2925.857 kb on + strand, within Rv2596at 2925.858 kb on - strand, within Rv2596at 2925.892 kb on + strand, within Rv2596at 2925.892 kb on + strand, within Rv2596at 2925.917 kb on + strand, within Rv2596at 2925.918 kb on - strand, within Rv2596at 2925.944 kb on + strand, within Rv2596at 2926.022 kb on + strand, within Rv2596at 2926.101 kb on - strandat 2926.286 kb on + strandat 2926.287 kb on - strandat 2926.291 kb on + strandat 2926.350 kb on + strandat 2926.350 kb on + strandat 2926.351 kb on - strandat 2926.351 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction pyruvate (C)
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2,925,462 + +0.2
2,925,463 - +0.3
2,925,857 + Rv2596 0.30 +0.6
2,925,858 - Rv2596 0.31 +0.8
2,925,892 + Rv2596 0.39 -0.1
2,925,892 + Rv2596 0.39 -0.6
2,925,917 + Rv2596 0.45 -0.2
2,925,918 - Rv2596 0.45 -0.2
2,925,944 + Rv2596 0.52 -0.4
2,926,022 + Rv2596 0.71 -0.3
2,926,101 - -0.7
2,926,286 + +0.2
2,926,287 - -0.0
2,926,291 + +0.1
2,926,350 + -0.8
2,926,350 + -0.5
2,926,351 - +0.9
2,926,351 - -0.0

Or see this region's nucleotide sequence