Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1059

Experiment: pyruvate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1058 and Rv1059 are separated by 75 nucleotidesRv1059 and Rv1060 are separated by 52 nucleotidesRv1060 and Rv1061 are separated by 33 nucleotides Rv1058: Rv1058 - Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 1,180,684 to 1,182,315 Rv1058 Rv1059: Rv1059 - Conserved protein, at 1,182,391 to 1,183,455 Rv1059 Rv1060: Rv1060 - Unknown protein, at 1,183,508 to 1,183,981 Rv1060 Rv1061: Rv1061 - Conserved protein, at 1,184,015 to 1,184,878 Rv1061 Position (kb) 1182 1183 1184Strain fitness (log2 ratio) -1 0 1 2at 1181.398 kb on + strand, within Rv1058at 1181.536 kb on + strand, within Rv1058at 1181.537 kb on - strand, within Rv1058at 1181.872 kb on + strand, within Rv1058at 1182.385 kb on - strandat 1182.485 kb on + strandat 1182.570 kb on + strand, within Rv1059at 1183.088 kb on + strand, within Rv1059at 1184.139 kb on + strand, within Rv1061at 1184.166 kb on + strand, within Rv1061at 1184.291 kb on - strand, within Rv1061at 1184.291 kb on - strand, within Rv1061at 1184.424 kb on + strand, within Rv1061

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Per-strain Table

Position Strand Gene LocusTag Fraction pyruvate (C)
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1,181,398 + Rv1058 0.44 +1.9
1,181,536 + Rv1058 0.52 -0.1
1,181,537 - Rv1058 0.52 -0.6
1,181,872 + Rv1058 0.73 -0.0
1,182,385 - -0.3
1,182,485 + +0.8
1,182,570 + Rv1059 0.17 +0.6
1,183,088 + Rv1059 0.65 +0.0
1,184,139 + Rv1061 0.14 -0.3
1,184,166 + Rv1061 0.17 -0.5
1,184,291 - Rv1061 0.32 -0.7
1,184,291 - Rv1061 0.32 +0.3
1,184,424 + Rv1061 0.47 -0.5

Or see this region's nucleotide sequence