Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3133c

Experiment: D-Glucose (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3132c and Rv3133c overlap by 4 nucleotidesRv3133c and Rv3134c are separated by 27 nucleotides Rv3132c: Rv3132c - Two component sensor histidine kinase DevS, at 3,497,529 to 3,499,265 Rv3132c Rv3133c: Rv3133c - Two component transcriptional regulatory protein DevR (probably LuxR/UhpA-family), at 3,499,262 to 3,499,915 Rv3133c Rv3134c: Rv3134c - Universal stress protein family protein, at 3,499,943 to 3,500,749 Rv3134c Position (kb) 3499 3500Strain fitness (log2 ratio) -1 0 1 2at 3498.755 kb on - strand, within Rv3132cat 3498.924 kb on + strand, within Rv3132cat 3499.011 kb on - strand, within Rv3132cat 3499.063 kb on - strand, within Rv3132cat 3499.365 kb on + strand, within Rv3133cat 3499.366 kb on - strand, within Rv3133cat 3499.366 kb on - strand, within Rv3133cat 3499.644 kb on - strand, within Rv3133cat 3499.665 kb on + strand, within Rv3133cat 3499.666 kb on - strand, within Rv3133cat 3499.910 kb on + strandat 3499.944 kb on + strandat 3499.945 kb on - strandat 3499.967 kb on - strandat 3499.967 kb on - strandat 3499.970 kb on + strandat 3499.989 kb on + strandat 3499.989 kb on + strandat 3499.990 kb on - strandat 3500.153 kb on + strand, within Rv3134cat 3500.153 kb on + strand, within Rv3134cat 3500.154 kb on - strand, within Rv3134cat 3500.154 kb on - strand, within Rv3134cat 3500.625 kb on + strand, within Rv3134cat 3500.626 kb on - strand, within Rv3134cat 3500.710 kb on + strandat 3500.774 kb on + strandat 3500.775 kb on - strandat 3500.801 kb on - strandat 3500.853 kb on + strandat 3500.909 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Glucose (C)
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3,498,755 - Rv3132c 0.71 -0.9
3,498,924 + Rv3132c 0.80 -0.8
3,499,011 - Rv3132c 0.85 +1.7
3,499,063 - Rv3132c 0.88 -0.2
3,499,365 + Rv3133c 0.16 -0.2
3,499,366 - Rv3133c 0.16 +0.1
3,499,366 - Rv3133c 0.16 -0.3
3,499,644 - Rv3133c 0.58 +0.6
3,499,665 + Rv3133c 0.62 +0.7
3,499,666 - Rv3133c 0.62 +2.7
3,499,910 + -0.2
3,499,944 + +0.6
3,499,945 - -0.3
3,499,967 - -0.2
3,499,967 - +0.3
3,499,970 + -0.3
3,499,989 + +0.1
3,499,989 + -1.0
3,499,990 - -0.5
3,500,153 + Rv3134c 0.26 +0.9
3,500,153 + Rv3134c 0.26 -0.1
3,500,154 - Rv3134c 0.26 -0.4
3,500,154 - Rv3134c 0.26 -0.2
3,500,625 + Rv3134c 0.85 -0.2
3,500,626 - Rv3134c 0.85 -0.2
3,500,710 + -0.2
3,500,774 + -1.2
3,500,775 - +0.3
3,500,801 - -0.1
3,500,853 + +0.3
3,500,909 + -0.3

Or see this region's nucleotide sequence