Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2236c

Experiment: D-Glucose (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2234 and Rv2235 overlap by 1 nucleotidesRv2235 and Rv2236c overlap by 19 nucleotidesRv2236c and Rv2237 are separated by 113 nucleotidesRv2237 and Rv2237A are separated by 94 nucleotides Rv2234: Rv2234 - Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase), at 2,507,146 to 2,507,637 Rv2234 Rv2235: Rv2235 - Probable conserved transmembrane protein, at 2,507,637 to 2,508,452 Rv2235 Rv2236c: Rv2236c - Probable cobalamin biosynthesis transmembrane protein CobD, at 2,508,434 to 2,509,375 Rv2236c Rv2237: Rv2237 - Conserved protein, at 2,509,489 to 2,510,256 Rv2237 Rv2237A: Rv2237A - Conserved protein, at 2,510,351 to 2,510,587 Rv2237A Position (kb) 2508 2509 2510Strain fitness (log2 ratio) -1 0 1at 2507.528 kb on - strand, within Rv2234at 2507.528 kb on - strand, within Rv2234at 2507.530 kb on + strand, within Rv2234at 2508.451 kb on - strandat 2509.208 kb on + strand, within Rv2236cat 2509.208 kb on + strand, within Rv2236cat 2509.236 kb on + strand, within Rv2236cat 2509.236 kb on + strand, within Rv2236cat 2509.236 kb on + strand, within Rv2236cat 2509.400 kb on + strandat 2509.401 kb on - strandat 2509.410 kb on + strandat 2509.414 kb on + strandat 2509.424 kb on + strandat 2509.433 kb on + strandat 2509.582 kb on + strand, within Rv2237at 2509.582 kb on + strand, within Rv2237at 2509.583 kb on - strand, within Rv2237at 2509.621 kb on + strand, within Rv2237at 2509.622 kb on - strand, within Rv2237at 2509.622 kb on - strand, within Rv2237at 2509.729 kb on + strand, within Rv2237at 2509.730 kb on - strand, within Rv2237at 2509.732 kb on - strand, within Rv2237at 2509.777 kb on + strand, within Rv2237at 2509.783 kb on + strand, within Rv2237at 2510.151 kb on - strand, within Rv2237at 2510.207 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Glucose (C)
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2,507,528 - Rv2234 0.78 -0.9
2,507,528 - Rv2234 0.78 +1.6
2,507,530 + Rv2234 0.78 +0.1
2,508,451 - -0.3
2,509,208 + Rv2236c 0.82 +0.2
2,509,208 + Rv2236c 0.82 +1.0
2,509,236 + Rv2236c 0.85 +0.6
2,509,236 + Rv2236c 0.85 -0.2
2,509,236 + Rv2236c 0.85 -0.5
2,509,400 + -0.0
2,509,401 - -0.3
2,509,410 + +0.5
2,509,414 + -0.9
2,509,424 + +0.3
2,509,433 + +0.4
2,509,582 + Rv2237 0.12 -1.0
2,509,582 + Rv2237 0.12 -0.4
2,509,583 - Rv2237 0.12 -0.8
2,509,621 + Rv2237 0.17 -0.3
2,509,622 - Rv2237 0.17 -0.1
2,509,622 - Rv2237 0.17 -0.4
2,509,729 + Rv2237 0.31 -0.2
2,509,730 - Rv2237 0.31 -0.4
2,509,732 - Rv2237 0.32 +0.2
2,509,777 + Rv2237 0.38 -0.2
2,509,783 + Rv2237 0.38 -0.1
2,510,151 - Rv2237 0.86 +0.8
2,510,207 - -1.4

Or see this region's nucleotide sequence