Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1474c

Experiment: D-Glucose (C)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1473 and Rv1473A are separated by 96 nucleotidesRv1473A and Rv1474c are separated by 68 nucleotidesRv1474c and Rv1475c are separated by 10 nucleotides Rv1473: Rv1473 - Probable macrolide-transport ATP-binding protein ABC transporter, at 1,660,656 to 1,662,284 Rv1473 Rv1473A: Rv1473A - Possible transcriptional regulatory protein, at 1,662,381 to 1,662,572 Rv1473A Rv1474c: Rv1474c - Probable transcriptional regulatory protein, at 1,662,641 to 1,663,204 Rv1474c Rv1475c: Rv1475c - Probable iron-regulated aconitate hydratase Acn (citrate hydro-lyase) (aconitase), at 1,663,215 to 1,666,046 Rv1475c Position (kb) 1662 1663 1664Strain fitness (log2 ratio) -1 0 1at 1661.841 kb on + strand, within Rv1473at 1662.288 kb on - strandat 1662.288 kb on - strandat 1662.347 kb on + strandat 1662.347 kb on + strandat 1662.348 kb on - strandat 1662.348 kb on - strandat 1662.353 kb on - strandat 1662.353 kb on - strandat 1662.486 kb on + strand, within Rv1473Aat 1662.494 kb on + strand, within Rv1473Aat 1662.987 kb on - strand, within Rv1474cat 1662.987 kb on - strand, within Rv1474cat 1662.987 kb on - strand, within Rv1474cat 1663.229 kb on + strandat 1663.231 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction D-Glucose (C)
remove
1,661,841 + Rv1473 0.73 +1.4
1,662,288 - -0.3
1,662,288 - -0.5
1,662,347 + +1.6
1,662,347 + +0.4
1,662,348 - -0.2
1,662,348 - -0.7
1,662,353 - +0.5
1,662,353 - +0.3
1,662,486 + Rv1473A 0.55 +0.4
1,662,494 + Rv1473A 0.59 -0.4
1,662,987 - Rv1474c 0.61 +0.0
1,662,987 - Rv1474c 0.61 +0.1
1,662,987 - Rv1474c 0.61 +1.2
1,663,229 + -0.6
1,663,231 - -0.5

Or see this region's nucleotide sequence