Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3668c

Experiment: D-Glucose (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3667 and Rv3668c are separated by 35 nucleotidesRv3668c and Rv3669 are separated by 345 nucleotidesRv3669 and Rv3670 are separated by 0 nucleotides Rv3667: Rv3667 - Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) (acetyl-CoA synthase) (acyl-activating enzyme) (acetate thiokinase) (acetyl-activating enzyme) (acetate--coenzyme A ligase) (acetyl-coenzyme A synthase), at 4,107,792 to 4,109,747 Rv3667 Rv3668c: Rv3668c - Possible protease, at 4,109,783 to 4,110,481 Rv3668c Rv3669: Rv3669 - Probable conserved transmembrane protein, at 4,110,827 to 4,111,345 Rv3669 Rv3670: Rv3670 - Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase), at 4,111,346 to 4,112,329 Rv3670 Position (kb) 4109 4110 4111Strain fitness (log2 ratio) -2 -1 0 1at 4109.196 kb on + strand, within Rv3667at 4109.299 kb on - strand, within Rv3667at 4109.299 kb on - strand, within Rv3667at 4109.326 kb on + strand, within Rv3667at 4109.350 kb on + strand, within Rv3667at 4109.510 kb on - strand, within Rv3667at 4109.520 kb on + strand, within Rv3667at 4109.520 kb on + strand, within Rv3667at 4109.521 kb on - strand, within Rv3667at 4109.521 kb on - strand, within Rv3667at 4109.608 kb on + strandat 4109.621 kb on - strandat 4109.793 kb on - strandat 4109.889 kb on + strand, within Rv3668cat 4109.890 kb on - strand, within Rv3668cat 4110.040 kb on + strand, within Rv3668cat 4110.184 kb on - strand, within Rv3668cat 4110.184 kb on - strand, within Rv3668cat 4110.330 kb on - strand, within Rv3668cat 4110.384 kb on - strand, within Rv3668cat 4110.384 kb on - strand, within Rv3668cat 4110.768 kb on - strandat 4111.343 kb on + strandat 4111.343 kb on + strandat 4111.343 kb on + strandat 4111.343 kb on + strandat 4111.343 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Glucose (C)
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4,109,196 + Rv3667 0.72 +0.4
4,109,299 - Rv3667 0.77 -0.6
4,109,299 - Rv3667 0.77 -0.6
4,109,326 + Rv3667 0.78 +0.4
4,109,350 + Rv3667 0.80 +1.0
4,109,510 - Rv3667 0.88 +0.2
4,109,520 + Rv3667 0.88 +0.3
4,109,520 + Rv3667 0.88 +0.2
4,109,521 - Rv3667 0.88 -0.4
4,109,521 - Rv3667 0.88 -0.1
4,109,608 + -0.4
4,109,621 - +0.2
4,109,793 - -0.3
4,109,889 + Rv3668c 0.15 -0.7
4,109,890 - Rv3668c 0.15 -0.3
4,110,040 + Rv3668c 0.37 -0.3
4,110,184 - Rv3668c 0.57 -0.3
4,110,184 - Rv3668c 0.57 -1.4
4,110,330 - Rv3668c 0.78 -0.7
4,110,384 - Rv3668c 0.86 -1.6
4,110,384 - Rv3668c 0.86 -0.7
4,110,768 - -0.6
4,111,343 + -0.4
4,111,343 + -1.9
4,111,343 + -0.7
4,111,343 + -0.4
4,111,343 + -1.4

Or see this region's nucleotide sequence