Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0050

Experiment: D-Glucose (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0048c and Rv0049 are separated by 133 nucleotidesRv0049 and Rv0050 are separated by 418 nucleotidesRv0050 and Rv0051 overlap by 4 nucleotides Rv0048c: Rv0048c - Possible membrane protein, at 51,828 to 52,697 Rv0048c Rv0049: Rv0049 - Conserved hypothetical protein, at 52,831 to 53,244 Rv0049 Rv0050: Rv0050 - Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase (peptidoglycan TGASE) + penicillin-sensitive transpeptidase (DD-transpeptidase), at 53,663 to 55,699 Rv0050 Rv0051: Rv0051 - Probable conserved transmembrane protein, at 55,696 to 57,378 Rv0051 Position (kb) 53 54 55 56Strain fitness (log2 ratio) -3 -2 -1 0 1at 52.706 kb on + strandat 52.706 kb on + strandat 52.706 kb on + strandat 52.707 kb on - strandat 52.707 kb on - strandat 52.709 kb on + strandat 52.746 kb on + strandat 52.775 kb on - strandat 52.797 kb on + strandat 52.798 kb on - strandat 52.829 kb on + strandat 52.829 kb on + strandat 52.837 kb on + strandat 52.837 kb on + strandat 52.837 kb on + strandat 53.114 kb on + strand, within Rv0049at 53.114 kb on + strand, within Rv0049at 53.152 kb on + strand, within Rv0049at 53.152 kb on + strand, within Rv0049at 53.152 kb on + strand, within Rv0049at 53.152 kb on + strand, within Rv0049at 54.173 kb on + strand, within Rv0050at 54.635 kb on + strand, within Rv0050at 54.635 kb on + strand, within Rv0050at 54.638 kb on + strand, within Rv0050at 54.759 kb on + strand, within Rv0050at 54.870 kb on - strand, within Rv0050at 55.086 kb on - strand, within Rv0050at 55.252 kb on - strand, within Rv0050at 55.560 kb on + strandat 55.796 kb on + strandat 56.008 kb on + strand, within Rv0051at 56.155 kb on + strand, within Rv0051at 56.157 kb on + strand, within Rv0051at 56.186 kb on - strand, within Rv0051at 56.229 kb on - strand, within Rv0051at 56.521 kb on + strand, within Rv0051at 56.540 kb on - strand, within Rv0051

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Glucose (C)
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52,706 + -0.2
52,706 + -0.3
52,706 + -0.1
52,707 - +0.1
52,707 - -0.3
52,709 + -0.2
52,746 + +0.3
52,775 - -1.0
52,797 + -0.8
52,798 - -0.1
52,829 + -0.6
52,829 + -0.5
52,837 + -0.1
52,837 + +0.5
52,837 + -0.4
53,114 + Rv0049 0.68 -0.1
53,114 + Rv0049 0.68 -0.1
53,152 + Rv0049 0.78 +0.7
53,152 + Rv0049 0.78 -1.2
53,152 + Rv0049 0.78 -1.2
53,152 + Rv0049 0.78 -1.0
54,173 + Rv0050 0.25 -1.2
54,635 + Rv0050 0.48 +1.7
54,635 + Rv0050 0.48 -0.5
54,638 + Rv0050 0.48 -1.4
54,759 + Rv0050 0.54 -0.1
54,870 - Rv0050 0.59 -3.0
55,086 - Rv0050 0.70 +0.9
55,252 - Rv0050 0.78 +1.1
55,560 + -0.3
55,796 + -0.3
56,008 + Rv0051 0.19 +0.1
56,155 + Rv0051 0.27 +0.1
56,157 + Rv0051 0.27 -0.1
56,186 - Rv0051 0.29 +0.1
56,229 - Rv0051 0.32 -0.3
56,521 + Rv0051 0.49 +0.2
56,540 - Rv0051 0.50 -0.3

Or see this region's nucleotide sequence