Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3545c

Experiment: acetate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3544c and Rv3545c overlap by 1 nucleotidesRv3545c and Rv3546 are separated by 111 nucleotides Rv3544c: Rv3544c - Probable acyl-CoA dehydrogenase FadE28, at 3,983,125 to 3,984,144 Rv3544c Rv3545c: Rv3545c - Probable cytochrome P450 125 Cyp125, at 3,984,144 to 3,985,445 Rv3545c Rv3546: Rv3546 - Probable acetyl-CoA acetyltransferase FadA5 (acetoacetyl-CoA thiolase), at 3,985,557 to 3,986,732 Rv3546 Position (kb) 3984 3985 3986Strain fitness (log2 ratio) -1 0 1at 3983.211 kb on - strandat 3983.214 kb on - strandat 3983.403 kb on - strand, within Rv3544cat 3983.403 kb on - strand, within Rv3544cat 3983.477 kb on + strand, within Rv3544cat 3983.523 kb on - strand, within Rv3544cat 3983.523 kb on - strand, within Rv3544cat 3983.652 kb on + strand, within Rv3544cat 3983.653 kb on - strand, within Rv3544cat 3983.995 kb on + strand, within Rv3544cat 3984.146 kb on - strandat 3984.164 kb on + strandat 3984.165 kb on - strandat 3984.172 kb on + strandat 3984.173 kb on - strandat 3984.191 kb on + strandat 3984.279 kb on + strand, within Rv3545cat 3984.280 kb on - strand, within Rv3545cat 3984.319 kb on + strand, within Rv3545cat 3984.320 kb on - strand, within Rv3545cat 3984.374 kb on + strand, within Rv3545cat 3984.374 kb on + strand, within Rv3545cat 3984.375 kb on - strand, within Rv3545cat 3984.452 kb on + strand, within Rv3545cat 3984.452 kb on + strand, within Rv3545cat 3984.565 kb on + strand, within Rv3545cat 3984.565 kb on + strand, within Rv3545cat 3984.565 kb on + strand, within Rv3545cat 3984.566 kb on - strand, within Rv3545cat 3984.823 kb on + strand, within Rv3545cat 3984.823 kb on + strand, within Rv3545cat 3985.172 kb on - strand, within Rv3545cat 3985.401 kb on - strandat 3985.410 kb on + strandat 3985.411 kb on - strandat 3985.411 kb on - strandat 3985.527 kb on + strandat 3986.412 kb on + strand, within Rv3546at 3986.412 kb on + strand, within Rv3546at 3986.413 kb on - strand, within Rv3546

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Per-strain Table

Position Strand Gene LocusTag Fraction acetate (C)
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3,983,211 - +0.0
3,983,214 - -0.2
3,983,403 - Rv3544c 0.27 -0.7
3,983,403 - Rv3544c 0.27 -0.0
3,983,477 + Rv3544c 0.35 +0.3
3,983,523 - Rv3544c 0.39 +0.1
3,983,523 - Rv3544c 0.39 -0.1
3,983,652 + Rv3544c 0.52 +0.7
3,983,653 - Rv3544c 0.52 -0.4
3,983,995 + Rv3544c 0.85 -0.9
3,984,146 - +0.1
3,984,164 + +1.5
3,984,165 - +1.7
3,984,172 + -0.9
3,984,173 - +0.0
3,984,191 + -0.4
3,984,279 + Rv3545c 0.10 -0.4
3,984,280 - Rv3545c 0.10 +0.0
3,984,319 + Rv3545c 0.13 -0.5
3,984,320 - Rv3545c 0.14 -1.5
3,984,374 + Rv3545c 0.18 -0.4
3,984,374 + Rv3545c 0.18 -0.5
3,984,375 - Rv3545c 0.18 +0.5
3,984,452 + Rv3545c 0.24 -0.2
3,984,452 + Rv3545c 0.24 +0.5
3,984,565 + Rv3545c 0.32 -0.2
3,984,565 + Rv3545c 0.32 -0.5
3,984,565 + Rv3545c 0.32 -0.8
3,984,566 - Rv3545c 0.32 -0.5
3,984,823 + Rv3545c 0.52 +0.3
3,984,823 + Rv3545c 0.52 -0.4
3,985,172 - Rv3545c 0.79 -1.2
3,985,401 - +0.3
3,985,410 + -0.4
3,985,411 - -0.6
3,985,411 - -0.6
3,985,527 + +0.3
3,986,412 + Rv3546 0.73 +0.7
3,986,412 + Rv3546 0.73 -0.5
3,986,413 - Rv3546 0.73 -1.0

Or see this region's nucleotide sequence