Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2502c

Experiment: acetate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2501c and Rv2502c are separated by 4 nucleotidesRv2502c and Rv2503c overlap by 4 nucleotidesRv2503c and Rv2504c overlap by 4 nucleotides Rv2501c: Rv2501c - Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA1: biotin carboxylase + biotin carboxyl carrier protein (BCCP), at 2,814,916 to 2,816,880 Rv2501c Rv2502c: Rv2502c - Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD1, at 2,816,885 to 2,818,474 Rv2502c Rv2503c: Rv2503c - Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (beta subunit) ScoB (3-oxo-acid:CoA transferase) (OXCT B) (succinyl CoA:3-oxoacid CoA-transferase), at 2,818,471 to 2,819,127 Rv2503c Rv2504c: Rv2504c - Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (alpha subunit) ScoA (3-oxo acid:CoA transferase) (OXCT A) (succinyl-CoA:3-oxoacid-coenzyme A transferase), at 2,819,124 to 2,819,870 Rv2504c Position (kb) 2816 2817 2818 2819Strain fitness (log2 ratio) -2 -1 0 1 2at 2816.078 kb on + strand, within Rv2501cat 2816.079 kb on - strand, within Rv2501cat 2816.166 kb on + strand, within Rv2501cat 2816.372 kb on - strand, within Rv2501cat 2816.809 kb on + strandat 2816.867 kb on - strandat 2817.229 kb on - strand, within Rv2502cat 2817.229 kb on - strand, within Rv2502cat 2817.913 kb on - strand, within Rv2502cat 2818.071 kb on + strand, within Rv2502cat 2818.087 kb on + strand, within Rv2502cat 2818.143 kb on + strand, within Rv2502cat 2818.144 kb on - strand, within Rv2502cat 2818.144 kb on - strand, within Rv2502cat 2818.248 kb on + strand, within Rv2502cat 2818.400 kb on - strandat 2818.400 kb on - strandat 2818.451 kb on + strandat 2818.523 kb on - strandat 2818.655 kb on - strand, within Rv2503cat 2818.781 kb on - strand, within Rv2503cat 2819.057 kb on + strand, within Rv2503cat 2819.058 kb on - strand, within Rv2503cat 2819.208 kb on + strand, within Rv2504cat 2819.318 kb on - strand, within Rv2504cat 2819.395 kb on + strand, within Rv2504cat 2819.396 kb on - strand, within Rv2504c

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Per-strain Table

Position Strand Gene LocusTag Fraction acetate (C)
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2,816,078 + Rv2501c 0.59 +0.4
2,816,079 - Rv2501c 0.59 +0.1
2,816,166 + Rv2501c 0.64 +0.9
2,816,372 - Rv2501c 0.74 -0.1
2,816,809 + +0.2
2,816,867 - +2.6
2,817,229 - Rv2502c 0.22 +0.1
2,817,229 - Rv2502c 0.22 +0.4
2,817,913 - Rv2502c 0.65 +1.3
2,818,071 + Rv2502c 0.75 +0.8
2,818,087 + Rv2502c 0.76 -0.1
2,818,143 + Rv2502c 0.79 +0.5
2,818,144 - Rv2502c 0.79 -0.4
2,818,144 - Rv2502c 0.79 +0.4
2,818,248 + Rv2502c 0.86 +0.4
2,818,400 - +0.8
2,818,400 - +0.6
2,818,451 + -0.6
2,818,523 - -0.3
2,818,655 - Rv2503c 0.28 -0.1
2,818,781 - Rv2503c 0.47 -0.5
2,819,057 + Rv2503c 0.89 +1.6
2,819,058 - Rv2503c 0.89 +1.6
2,819,208 + Rv2504c 0.11 -0.3
2,819,318 - Rv2504c 0.26 +0.4
2,819,395 + Rv2504c 0.36 +2.2
2,819,396 - Rv2504c 0.36 -1.8

Or see this region's nucleotide sequence