Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2477c

Experiment: acetate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2476c and Rv2477c are separated by 103 nucleotidesRv2477c and Rv2478c are separated by 80 nucleotidesRv2478c and Rv2479c are separated by 48 nucleotides Rv2476c: Rv2476c - Probable NAD-dependent glutamate dehydrogenase Gdh (NAD-Gdh) (NAD-dependent glutamic dehydrogenase), at 2,777,388 to 2,782,262 Rv2476c Rv2477c: Rv2477c - Probable macrolide-transport ATP-binding protein ABC transporter, at 2,782,366 to 2,784,042 Rv2477c Rv2478c: Rv2478c - Conserved hypothetical protein, at 2,784,123 to 2,784,608 Rv2478c Rv2479c: Rv2479c - Probable transposase, at 2,784,657 to 2,785,643 Rv2479c Position (kb) 2782 2783 2784 2785Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2781.386 kb on - strand, within Rv2476cat 2781.404 kb on - strand, within Rv2476cat 2782.061 kb on - strandat 2782.160 kb on - strandat 2782.172 kb on - strandat 2782.361 kb on + strandat 2782.361 kb on + strandat 2782.362 kb on - strandat 2782.362 kb on - strandat 2784.091 kb on + strandat 2784.091 kb on + strandat 2784.092 kb on - strandat 2784.092 kb on - strandat 2784.092 kb on - strandat 2784.125 kb on - strandat 2784.274 kb on + strand, within Rv2478cat 2784.388 kb on + strand, within Rv2478cat 2784.388 kb on + strand, within Rv2478cat 2784.476 kb on + strand, within Rv2478c

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Per-strain Table

Position Strand Gene LocusTag Fraction acetate (C)
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2,781,386 - Rv2476c 0.82 -2.0
2,781,404 - Rv2476c 0.82 -2.9
2,782,061 - -0.5
2,782,160 - -0.4
2,782,172 - -0.9
2,782,361 + -1.4
2,782,361 + +1.6
2,782,362 - +0.2
2,782,362 - -0.2
2,784,091 + -0.7
2,784,091 + -0.0
2,784,092 - +0.6
2,784,092 - +2.1
2,784,092 - +0.1
2,784,125 - -0.5
2,784,274 + Rv2478c 0.31 +0.6
2,784,388 + Rv2478c 0.55 -0.2
2,784,388 + Rv2478c 0.55 +0.1
2,784,476 + Rv2478c 0.73 -0.2

Or see this region's nucleotide sequence