Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1427c

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1426c and Rv1427c overlap by 1 nucleotidesRv1427c and Rv1428c are separated by 3 nucleotidesRv1428c and Rv1429 are separated by 118 nucleotides Rv1426c: Rv1426c - Probable esterase LipO, at 1,601,059 to 1,602,321 Rv1426c Rv1427c: Rv1427c - Possible long-chain-fatty-acid--CoA ligase FadD12 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 1,602,321 to 1,603,928 Rv1427c Rv1428c: Rv1428c - Conserved hypothetical protein, at 1,603,932 to 1,604,759 Rv1428c Rv1429: Rv1429 - Conserved protein, at 1,604,878 to 1,606,146 Rv1429 Position (kb) 1602 1603 1604Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1601.672 kb on + strand, within Rv1426cat 1601.673 kb on - strand, within Rv1426cat 1601.673 kb on - strand, within Rv1426cat 1601.858 kb on + strand, within Rv1426cat 1601.858 kb on + strand, within Rv1426cat 1601.934 kb on + strand, within Rv1426cat 1601.970 kb on + strand, within Rv1426cat 1601.975 kb on + strand, within Rv1426cat 1602.164 kb on + strand, within Rv1426cat 1602.165 kb on - strand, within Rv1426cat 1602.418 kb on + strandat 1602.418 kb on + strandat 1602.418 kb on + strandat 1602.514 kb on + strand, within Rv1427cat 1602.595 kb on + strand, within Rv1427cat 1602.595 kb on + strand, within Rv1427cat 1602.728 kb on + strand, within Rv1427cat 1602.729 kb on - strand, within Rv1427cat 1602.729 kb on - strand, within Rv1427cat 1602.731 kb on - strand, within Rv1427cat 1602.760 kb on + strand, within Rv1427cat 1603.392 kb on + strand, within Rv1427cat 1603.392 kb on + strand, within Rv1427cat 1603.505 kb on - strand, within Rv1427cat 1603.922 kb on + strandat 1603.922 kb on + strandat 1603.998 kb on + strandat 1603.998 kb on + strandat 1603.999 kb on - strandat 1603.999 kb on - strandat 1604.064 kb on + strand, within Rv1428cat 1604.064 kb on + strand, within Rv1428cat 1604.218 kb on + strand, within Rv1428cat 1604.218 kb on + strand, within Rv1428cat 1604.218 kb on + strand, within Rv1428cat 1604.219 kb on - strand, within Rv1428cat 1604.219 kb on - strand, within Rv1428cat 1604.293 kb on + strand, within Rv1428cat 1604.525 kb on - strand, within Rv1428cat 1604.641 kb on + strand, within Rv1428cat 1604.642 kb on - strand, within Rv1428cat 1604.642 kb on - strand, within Rv1428cat 1604.642 kb on - strand, within Rv1428cat 1604.670 kb on + strand, within Rv1428cat 1604.671 kb on - strand, within Rv1428cat 1604.808 kb on - strandat 1604.853 kb on + strandat 1604.923 kb on - strandat 1604.923 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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1,601,672 + Rv1426c 0.49 -0.1
1,601,673 - Rv1426c 0.49 -0.0
1,601,673 - Rv1426c 0.49 -0.4
1,601,858 + Rv1426c 0.63 +1.8
1,601,858 + Rv1426c 0.63 +2.8
1,601,934 + Rv1426c 0.69 -0.3
1,601,970 + Rv1426c 0.72 -0.1
1,601,975 + Rv1426c 0.73 -0.3
1,602,164 + Rv1426c 0.87 -0.8
1,602,165 - Rv1426c 0.88 +1.8
1,602,418 + +3.4
1,602,418 + -0.2
1,602,418 + +0.5
1,602,514 + Rv1427c 0.12 -0.4
1,602,595 + Rv1427c 0.17 -0.3
1,602,595 + Rv1427c 0.17 +0.3
1,602,728 + Rv1427c 0.25 +0.4
1,602,729 - Rv1427c 0.25 -0.3
1,602,729 - Rv1427c 0.25 +0.2
1,602,731 - Rv1427c 0.25 +0.3
1,602,760 + Rv1427c 0.27 +0.3
1,603,392 + Rv1427c 0.67 -0.3
1,603,392 + Rv1427c 0.67 +0.0
1,603,505 - Rv1427c 0.74 -0.1
1,603,922 + +0.3
1,603,922 + -0.3
1,603,998 + -0.5
1,603,998 + +0.0
1,603,999 - -0.0
1,603,999 - -0.2
1,604,064 + Rv1428c 0.16 -0.2
1,604,064 + Rv1428c 0.16 -2.3
1,604,218 + Rv1428c 0.35 +1.5
1,604,218 + Rv1428c 0.35 -0.3
1,604,218 + Rv1428c 0.35 -0.2
1,604,219 - Rv1428c 0.35 +1.8
1,604,219 - Rv1428c 0.35 -0.2
1,604,293 + Rv1428c 0.44 -0.2
1,604,525 - Rv1428c 0.72 -0.0
1,604,641 + Rv1428c 0.86 -0.8
1,604,642 - Rv1428c 0.86 -0.2
1,604,642 - Rv1428c 0.86 +1.1
1,604,642 - Rv1428c 0.86 +0.6
1,604,670 + Rv1428c 0.89 -2.2
1,604,671 - Rv1428c 0.89 +1.4
1,604,808 - -0.5
1,604,853 + +0.8
1,604,923 - -0.4
1,604,923 - -1.0

Or see this region's nucleotide sequence