Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1141c

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1140 and Rv1141c are separated by 7 nucleotidesRv1141c and Rv1142c are separated by 142 nucleotides Rv1140: Rv1140 - Probable integral membrane protein, at 1,267,347 to 1,268,195 Rv1140 Rv1141c: Rv1141c - Probable enoyl-CoA hydratase EchA11 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,268,203 to 1,269,009 Rv1141c Rv1142c: Rv1142c - Probable enoyl-CoA hydratase EchA10 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,269,152 to 1,269,958 Rv1142c Position (kb) 1268 1269 1270Strain fitness (log2 ratio) -1 0 1at 1267.319 kb on - strandat 1267.804 kb on + strand, within Rv1140at 1267.805 kb on - strand, within Rv1140at 1268.542 kb on + strand, within Rv1141cat 1268.576 kb on - strand, within Rv1141cat 1268.608 kb on - strand, within Rv1141cat 1268.620 kb on + strand, within Rv1141cat 1268.716 kb on + strand, within Rv1141cat 1268.784 kb on + strand, within Rv1141cat 1268.784 kb on + strand, within Rv1141cat 1268.785 kb on - strand, within Rv1141cat 1268.785 kb on - strand, within Rv1141cat 1268.984 kb on - strandat 1269.022 kb on - strandat 1269.022 kb on - strandat 1269.022 kb on - strandat 1269.050 kb on - strandat 1269.099 kb on + strandat 1269.100 kb on - strandat 1269.220 kb on + strandat 1269.387 kb on + strand, within Rv1142cat 1269.454 kb on + strand, within Rv1142cat 1269.455 kb on - strand, within Rv1142cat 1269.455 kb on - strand, within Rv1142cat 1269.569 kb on + strand, within Rv1142cat 1269.569 kb on + strand, within Rv1142cat 1269.647 kb on + strand, within Rv1142cat 1269.648 kb on - strand, within Rv1142cat 1269.648 kb on - strand, within Rv1142cat 1269.948 kb on + strandat 1269.964 kb on + strandat 1270.005 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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1,267,319 - -0.1
1,267,804 + Rv1140 0.54 -0.5
1,267,805 - Rv1140 0.54 +0.2
1,268,542 + Rv1141c 0.42 -0.1
1,268,576 - Rv1141c 0.46 +0.7
1,268,608 - Rv1141c 0.50 +0.0
1,268,620 + Rv1141c 0.52 +0.7
1,268,716 + Rv1141c 0.64 -1.7
1,268,784 + Rv1141c 0.72 -0.4
1,268,784 + Rv1141c 0.72 -0.3
1,268,785 - Rv1141c 0.72 -0.2
1,268,785 - Rv1141c 0.72 -0.1
1,268,984 - -0.0
1,269,022 - -0.2
1,269,022 - +0.2
1,269,022 - +0.2
1,269,050 - -0.2
1,269,099 + +1.2
1,269,100 - -1.2
1,269,220 + +0.2
1,269,387 + Rv1142c 0.29 -0.0
1,269,454 + Rv1142c 0.37 -0.0
1,269,455 - Rv1142c 0.38 -0.4
1,269,455 - Rv1142c 0.38 -0.1
1,269,569 + Rv1142c 0.52 +0.1
1,269,569 + Rv1142c 0.52 -1.5
1,269,647 + Rv1142c 0.61 -0.5
1,269,648 - Rv1142c 0.61 -0.5
1,269,648 - Rv1142c 0.61 -0.6
1,269,948 + +0.1
1,269,964 + -0.4
1,270,005 + +1.0

Or see this region's nucleotide sequence