Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0223c

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0221 and Rv0222 are separated by 30 nucleotidesRv0222 and Rv0223c are separated by 5 nucleotidesRv0223c and Rv0224c are separated by 98 nucleotidesRv0224c and Rv0225 are separated by 35 nucleotides Rv0221: Rv0221 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 264,067 to 265,476 Rv0221 Rv0222: Rv0222 - Probable enoyl-CoA hydratase EchA1 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 265,507 to 266,295 Rv0222 Rv0223c: Rv0223c - Probable aldehyde dehydrogenase, at 266,301 to 267,764 Rv0223c Rv0224c: Rv0224c - Possible methyltransferase (methylase), at 267,863 to 268,627 Rv0224c Rv0225: Rv0225 - Possible conserved protein, at 268,663 to 269,817 Rv0225 Position (kb) 266 267 268Strain fitness (log2 ratio) -2 -1 0 1at 265.315 kb on + strand, within Rv0221at 265.316 kb on - strand, within Rv0221at 265.507 kb on - strandat 265.832 kb on - strand, within Rv0222at 265.976 kb on - strand, within Rv0222at 266.016 kb on - strand, within Rv0222at 266.016 kb on - strand, within Rv0222at 266.152 kb on - strand, within Rv0222at 266.184 kb on + strand, within Rv0222at 266.449 kb on + strand, within Rv0223cat 266.527 kb on + strand, within Rv0223cat 266.573 kb on - strand, within Rv0223cat 266.660 kb on + strand, within Rv0223cat 266.740 kb on + strand, within Rv0223cat 266.740 kb on + strand, within Rv0223cat 267.006 kb on + strand, within Rv0223cat 267.080 kb on + strand, within Rv0223cat 267.409 kb on + strand, within Rv0223cat 267.409 kb on + strand, within Rv0223cat 267.658 kb on + strandat 267.659 kb on - strandat 267.682 kb on - strandat 267.764 kb on + strandat 267.764 kb on + strandat 267.765 kb on - strandat 267.765 kb on - strandat 267.865 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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265,315 + Rv0221 0.89 -1.1
265,316 - Rv0221 0.89 -0.2
265,507 - -0.2
265,832 - Rv0222 0.41 -0.6
265,976 - Rv0222 0.59 -0.2
266,016 - Rv0222 0.65 -0.6
266,016 - Rv0222 0.65 -0.3
266,152 - Rv0222 0.82 -0.1
266,184 + Rv0222 0.86 -0.4
266,449 + Rv0223c 0.10 -0.1
266,527 + Rv0223c 0.15 -0.2
266,573 - Rv0223c 0.19 -0.3
266,660 + Rv0223c 0.25 -0.1
266,740 + Rv0223c 0.30 +0.2
266,740 + Rv0223c 0.30 +0.1
267,006 + Rv0223c 0.48 -2.4
267,080 + Rv0223c 0.53 -0.3
267,409 + Rv0223c 0.76 -0.6
267,409 + Rv0223c 0.76 +0.4
267,658 + -0.3
267,659 - +0.1
267,682 - -0.2
267,764 + +0.6
267,764 + -0.1
267,765 - -0.4
267,765 - -0.2
267,865 - +0.2

Or see this region's nucleotide sequence