Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3477

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3476c and Rv3477 are separated by 372 nucleotidesRv3477 and Rv3478 are separated by 36 nucleotides Rv3476c: Rv3476c - Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter), at 3,892,371 to 3,893,720 Rv3476c Rv3477: Rv3477 - PE family protein PE31, at 3,894,093 to 3,894,389 Rv3477 Rv3478: Rv3478 - PE family protein PPE60, at 3,894,426 to 3,895,607 Rv3478 Position (kb) 3894 3895Strain fitness (log2 ratio) -2 -1 0 1at 3893.284 kb on + strand, within Rv3476cat 3893.285 kb on - strand, within Rv3476cat 3893.346 kb on - strand, within Rv3476cat 3893.513 kb on + strand, within Rv3476cat 3893.514 kb on - strand, within Rv3476cat 3893.536 kb on + strand, within Rv3476cat 3893.585 kb on - strand, within Rv3476cat 3893.588 kb on + strandat 3893.608 kb on + strandat 3893.609 kb on - strandat 3893.617 kb on + strandat 3893.617 kb on + strandat 3894.273 kb on + strand, within Rv3477at 3894.348 kb on + strand, within Rv3477at 3894.846 kb on + strand, within Rv3478at 3894.847 kb on - strand, within Rv3478at 3894.847 kb on - strand, within Rv3478at 3894.883 kb on - strand, within Rv3478at 3895.082 kb on - strand, within Rv3478at 3895.232 kb on - strand, within Rv3478

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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3,893,284 + Rv3476c 0.68 -0.0
3,893,285 - Rv3476c 0.68 +0.4
3,893,346 - Rv3476c 0.72 +0.4
3,893,513 + Rv3476c 0.85 -0.7
3,893,514 - Rv3476c 0.85 +0.2
3,893,536 + Rv3476c 0.86 -1.1
3,893,585 - Rv3476c 0.90 +0.1
3,893,588 + +0.2
3,893,608 + +0.1
3,893,609 - +0.4
3,893,617 + +0.2
3,893,617 + -0.8
3,894,273 + Rv3477 0.61 -0.1
3,894,348 + Rv3477 0.86 -1.0
3,894,846 + Rv3478 0.36 -1.0
3,894,847 - Rv3478 0.36 -0.7
3,894,847 - Rv3478 0.36 -2.3
3,894,883 - Rv3478 0.39 -2.1
3,895,082 - Rv3478 0.55 +0.0
3,895,232 - Rv3478 0.68 -2.3

Or see this region's nucleotide sequence