Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3376

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3375 and Rv3376 are separated by 107 nucleotidesRv3376 and Rv3377c are separated by 38 nucleotides Rv3375: Rv3375 - Probable amidase AmiD (acylamidase) (acylase), at 3,788,621 to 3,790,048 Rv3375 Rv3376: Rv3376 - Conserved hypothetical protein, at 3,790,156 to 3,790,809 Rv3376 Rv3377c: Rv3377c - Halimadienyl diphosphate synthase, at 3,790,848 to 3,792,353 Rv3377c Position (kb) 3790 3791Strain fitness (log2 ratio) -1 0 1at 3789.359 kb on - strand, within Rv3375at 3790.115 kb on - strandat 3790.165 kb on - strandat 3790.397 kb on + strand, within Rv3376at 3790.411 kb on + strand, within Rv3376at 3790.412 kb on - strand, within Rv3376at 3790.412 kb on - strand, within Rv3376at 3790.433 kb on - strand, within Rv3376at 3790.616 kb on - strand, within Rv3376at 3790.720 kb on + strand, within Rv3376at 3790.721 kb on - strand, within Rv3376at 3790.885 kb on - strandat 3790.898 kb on + strandat 3790.898 kb on + strandat 3790.899 kb on - strandat 3790.903 kb on - strandat 3790.903 kb on - strandat 3790.918 kb on + strandat 3790.948 kb on + strandat 3790.971 kb on + strandat 3790.972 kb on - strandat 3791.054 kb on - strand, within Rv3377cat 3791.162 kb on - strand, within Rv3377cat 3791.406 kb on + strand, within Rv3377cat 3791.553 kb on + strand, within Rv3377cat 3791.553 kb on + strand, within Rv3377cat 3791.554 kb on - strand, within Rv3377cat 3791.554 kb on - strand, within Rv3377c

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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3,789,359 - Rv3375 0.52 +0.6
3,790,115 - +0.2
3,790,165 - -0.3
3,790,397 + Rv3376 0.37 -0.9
3,790,411 + Rv3376 0.39 -0.7
3,790,412 - Rv3376 0.39 +0.6
3,790,412 - Rv3376 0.39 -0.7
3,790,433 - Rv3376 0.42 -0.7
3,790,616 - Rv3376 0.70 -0.5
3,790,720 + Rv3376 0.86 -0.2
3,790,721 - Rv3376 0.86 -1.4
3,790,885 - -0.3
3,790,898 + +0.7
3,790,898 + -0.4
3,790,899 - +0.1
3,790,903 - -0.3
3,790,903 - -0.5
3,790,918 + +0.3
3,790,948 + +0.9
3,790,971 + -0.2
3,790,972 - -0.5
3,791,054 - Rv3377c 0.14 +0.1
3,791,162 - Rv3377c 0.21 +0.1
3,791,406 + Rv3377c 0.37 -0.7
3,791,553 + Rv3377c 0.47 -0.7
3,791,553 + Rv3377c 0.47 -0.5
3,791,554 - Rv3377c 0.47 -0.2
3,791,554 - Rv3377c 0.47 +1.1

Or see this region's nucleotide sequence