Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3267

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3266c and Rv3267 are separated by 75 nucleotidesRv3267 and Rv3268 are separated by 38 nucleotidesRv3268 and Rv3269 are separated by 124 nucleotides Rv3266c: Rv3266c - dTDP-6-deoxy-L-lyxo-4-hexulose reductase RmlD (dTDP-rhamnose modification protein) (dTDP-rhamnose biosynthesis protein) (dTDP-rhamnose synthase), at 3,646,895 to 3,647,809 Rv3266c Rv3267: Rv3267 - Conserved protein (CPSA-related protein), at 3,647,885 to 3,649,381 Rv3267 Rv3268: Rv3268 - Conserved hypothetical protein, at 3,649,420 to 3,650,109 Rv3268 Rv3269: Rv3269 - Conserved protein, at 3,650,234 to 3,650,515 Rv3269 Position (kb) 3647 3648 3649 3650Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3647.882 kb on - strandat 3647.882 kb on - strandat 3648.246 kb on - strand, within Rv3267at 3648.269 kb on - strand, within Rv3267at 3648.269 kb on - strand, within Rv3267at 3649.229 kb on + strand, within Rv3267at 3649.258 kb on + strandat 3649.457 kb on - strandat 3649.459 kb on + strandat 3649.460 kb on - strandat 3649.460 kb on - strandat 3649.460 kb on - strandat 3649.583 kb on + strand, within Rv3268at 3649.649 kb on + strand, within Rv3268at 3649.810 kb on + strand, within Rv3268at 3649.829 kb on + strand, within Rv3268at 3649.844 kb on + strand, within Rv3268at 3649.844 kb on + strand, within Rv3268at 3649.845 kb on - strand, within Rv3268at 3649.882 kb on - strand, within Rv3268at 3650.147 kb on + strandat 3650.167 kb on + strandat 3650.241 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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3,647,882 - -2.3
3,647,882 - -0.1
3,648,246 - Rv3267 0.24 -0.2
3,648,269 - Rv3267 0.26 -1.7
3,648,269 - Rv3267 0.26 -2.3
3,649,229 + Rv3267 0.90 -1.3
3,649,258 + -3.2
3,649,457 - +0.2
3,649,459 + -1.0
3,649,460 - +0.6
3,649,460 - +1.9
3,649,460 - +0.2
3,649,583 + Rv3268 0.24 +0.2
3,649,649 + Rv3268 0.33 +0.2
3,649,810 + Rv3268 0.57 -0.1
3,649,829 + Rv3268 0.59 +0.2
3,649,844 + Rv3268 0.61 +0.1
3,649,844 + Rv3268 0.61 -0.6
3,649,845 - Rv3268 0.62 +0.4
3,649,882 - Rv3268 0.67 +0.2
3,650,147 + +1.9
3,650,167 + -0.4
3,650,241 + -0.3

Or see this region's nucleotide sequence