Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3143

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3141 and Rv3142c are separated by 51 nucleotidesRv3142c and Rv3143 are separated by 107 nucleotidesRv3143 and Rv3144c are separated by 32 nucleotides Rv3141: Rv3141 - Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin), at 3,508,095 to 3,509,066 Rv3141 Rv3142c: Rv3142c - Hypothetical protein, at 3,509,118 to 3,509,546 Rv3142c Rv3143: Rv3143 - Probable response regulator, at 3,509,654 to 3,510,055 Rv3143 Rv3144c: Rv3144c - PPE family protein PPE52, at 3,510,088 to 3,511,317 Rv3144c Position (kb) 3509 3510 3511Strain fitness (log2 ratio) -3 -2 -1 0 1at 3508.723 kb on + strand, within Rv3141at 3508.871 kb on - strand, within Rv3141at 3508.943 kb on - strand, within Rv3141at 3508.943 kb on - strand, within Rv3141at 3508.980 kb on + strandat 3509.047 kb on + strandat 3509.047 kb on + strandat 3509.050 kb on + strandat 3509.051 kb on - strandat 3509.143 kb on - strandat 3509.210 kb on - strand, within Rv3142cat 3509.210 kb on - strand, within Rv3142cat 3509.296 kb on + strand, within Rv3142cat 3509.296 kb on + strand, within Rv3142cat 3509.425 kb on - strand, within Rv3142cat 3509.430 kb on + strand, within Rv3142cat 3509.452 kb on + strand, within Rv3142cat 3509.453 kb on - strand, within Rv3142cat 3509.453 kb on - strand, within Rv3142cat 3509.489 kb on + strand, within Rv3142cat 3509.489 kb on + strand, within Rv3142cat 3509.546 kb on + strandat 3509.546 kb on + strandat 3509.546 kb on + strandat 3509.547 kb on - strandat 3509.547 kb on - strandat 3509.548 kb on + strandat 3509.548 kb on + strandat 3509.549 kb on - strandat 3509.549 kb on - strandat 3509.574 kb on + strandat 3509.575 kb on - strandat 3509.575 kb on - strandat 3509.583 kb on + strandat 3509.583 kb on + strandat 3509.584 kb on - strandat 3509.641 kb on - strandat 3509.691 kb on - strandat 3509.771 kb on + strand, within Rv3143at 3509.803 kb on - strand, within Rv3143at 3510.136 kb on + strandat 3510.226 kb on + strand, within Rv3144cat 3510.227 kb on - strand, within Rv3144cat 3510.227 kb on - strand, within Rv3144cat 3510.439 kb on - strand, within Rv3144cat 3510.528 kb on + strand, within Rv3144cat 3510.590 kb on - strand, within Rv3144cat 3510.630 kb on + strand, within Rv3144cat 3510.651 kb on - strand, within Rv3144cat 3510.857 kb on + strand, within Rv3144cat 3510.899 kb on + strand, within Rv3144c

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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3,508,723 + Rv3141 0.65 -0.9
3,508,871 - Rv3141 0.80 +0.2
3,508,943 - Rv3141 0.87 -0.0
3,508,943 - Rv3141 0.87 -0.5
3,508,980 + -1.8
3,509,047 + -0.4
3,509,047 + -0.0
3,509,050 + +0.2
3,509,051 - -0.5
3,509,143 - -0.5
3,509,210 - Rv3142c 0.21 -0.2
3,509,210 - Rv3142c 0.21 +0.3
3,509,296 + Rv3142c 0.41 +1.2
3,509,296 + Rv3142c 0.41 +1.2
3,509,425 - Rv3142c 0.72 -0.1
3,509,430 + Rv3142c 0.73 -0.4
3,509,452 + Rv3142c 0.78 -0.6
3,509,453 - Rv3142c 0.78 -1.3
3,509,453 - Rv3142c 0.78 +0.4
3,509,489 + Rv3142c 0.86 +0.0
3,509,489 + Rv3142c 0.86 -0.1
3,509,546 + -0.5
3,509,546 + +0.2
3,509,546 + -0.7
3,509,547 - -0.4
3,509,547 - -1.3
3,509,548 + +0.3
3,509,548 + +0.4
3,509,549 - -2.9
3,509,549 - -1.4
3,509,574 + +0.3
3,509,575 - +0.3
3,509,575 - +1.5
3,509,583 + -1.1
3,509,583 + -1.1
3,509,584 - +0.3
3,509,641 - -1.5
3,509,691 - -3.1
3,509,771 + Rv3143 0.29 -2.3
3,509,803 - Rv3143 0.37 -0.4
3,510,136 + +0.9
3,510,226 + Rv3144c 0.11 -0.1
3,510,227 - Rv3144c 0.11 -1.1
3,510,227 - Rv3144c 0.11 -1.0
3,510,439 - Rv3144c 0.29 -0.4
3,510,528 + Rv3144c 0.36 +1.6
3,510,590 - Rv3144c 0.41 -0.5
3,510,630 + Rv3144c 0.44 +0.0
3,510,651 - Rv3144c 0.46 -0.9
3,510,857 + Rv3144c 0.63 +0.2
3,510,899 + Rv3144c 0.66 +0.4

Or see this region's nucleotide sequence