Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3085

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3083 and Rv3084 are separated by 5 nucleotidesRv3084 and Rv3085 overlap by 4 nucleotidesRv3085 and Rv3086 are separated by 30 nucleotides Rv3083: Rv3083 - Probable monooxygenase (hydroxylase), at 3,448,504 to 3,449,991 Rv3083 Rv3084: Rv3084 - Probable acetyl-hydrolase/esterase LipR, at 3,449,997 to 3,450,923 Rv3084 Rv3085: Rv3085 - Probable short-chain type dehydrogenase/reductase, at 3,450,920 to 3,451,750 Rv3085 Rv3086: Rv3086 - Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase), at 3,451,781 to 3,452,887 Rv3086 Position (kb) 3450 3451 3452Strain fitness (log2 ratio) -2 -1 0 1at 3450.029 kb on - strandat 3450.029 kb on - strandat 3450.031 kb on + strandat 3450.031 kb on + strandat 3450.319 kb on - strand, within Rv3084at 3450.619 kb on + strand, within Rv3084at 3450.620 kb on - strand, within Rv3084at 3450.620 kb on - strand, within Rv3084at 3450.647 kb on + strand, within Rv3084at 3451.181 kb on + strand, within Rv3085at 3451.203 kb on - strand, within Rv3085at 3451.697 kb on + strandat 3451.697 kb on + strandat 3451.756 kb on + strandat 3451.756 kb on + strandat 3451.881 kb on - strandat 3451.881 kb on - strandat 3451.881 kb on - strandat 3451.881 kb on - strandat 3451.933 kb on - strand, within Rv3086at 3452.066 kb on + strand, within Rv3086at 3452.351 kb on + strand, within Rv3086at 3452.351 kb on + strand, within Rv3086at 3452.407 kb on + strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.408 kb on - strand, within Rv3086at 3452.411 kb on + strand, within Rv3086at 3452.412 kb on - strand, within Rv3086at 3452.412 kb on - strand, within Rv3086

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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3,450,029 - -0.1
3,450,029 - -0.1
3,450,031 + -0.8
3,450,031 + -1.1
3,450,319 - Rv3084 0.35 -0.4
3,450,619 + Rv3084 0.67 -0.5
3,450,620 - Rv3084 0.67 -0.3
3,450,620 - Rv3084 0.67 +0.1
3,450,647 + Rv3084 0.70 -0.5
3,451,181 + Rv3085 0.31 +1.3
3,451,203 - Rv3085 0.34 -2.3
3,451,697 + +0.0
3,451,697 + +0.2
3,451,756 + -0.1
3,451,756 + +0.5
3,451,881 - +1.7
3,451,881 - +0.1
3,451,881 - -0.6
3,451,881 - -0.5
3,451,933 - Rv3086 0.14 -0.6
3,452,066 + Rv3086 0.26 -1.1
3,452,351 + Rv3086 0.51 -0.2
3,452,351 + Rv3086 0.51 +0.6
3,452,407 + Rv3086 0.57 -1.8
3,452,408 - Rv3086 0.57 -0.5
3,452,408 - Rv3086 0.57 +0.3
3,452,408 - Rv3086 0.57 +0.1
3,452,408 - Rv3086 0.57 -0.5
3,452,411 + Rv3086 0.57 +0.7
3,452,412 - Rv3086 0.57 -0.1
3,452,412 - Rv3086 0.57 +0.5

Or see this region's nucleotide sequence