Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2506

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2505c and Rv2506 are separated by 115 nucleotidesRv2506 and Rv2507 are separated by 78 nucleotidesRv2507 and Rv2508c overlap by 4 nucleotides Rv2505c: Rv2505c - Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 2,819,953 to 2,821,596 Rv2505c Rv2506: Rv2506 - Probable transcriptional regulatory protein (probably TetR-family), at 2,821,712 to 2,822,359 Rv2506 Rv2507: Rv2507 - Possible conserved proline rich membrane protein, at 2,822,438 to 2,823,259 Rv2507 Rv2508c: Rv2508c - Probable conserved integral membrane leucine and alanine rich protein, at 2,823,256 to 2,824,593 Rv2508c Position (kb) 2821 2822 2823Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2820.749 kb on + strand, within Rv2505cat 2820.862 kb on + strand, within Rv2505cat 2820.881 kb on + strand, within Rv2505cat 2820.920 kb on + strand, within Rv2505cat 2820.945 kb on - strand, within Rv2505cat 2821.014 kb on - strand, within Rv2505cat 2821.179 kb on - strand, within Rv2505cat 2821.242 kb on - strand, within Rv2505cat 2821.282 kb on + strand, within Rv2505cat 2821.430 kb on + strand, within Rv2505cat 2821.557 kb on - strandat 2821.557 kb on - strandat 2821.616 kb on + strandat 2821.647 kb on + strandat 2821.648 kb on - strandat 2821.648 kb on - strandat 2821.658 kb on - strandat 2821.672 kb on + strandat 2821.898 kb on + strand, within Rv2506at 2822.091 kb on + strand, within Rv2506at 2822.144 kb on + strand, within Rv2506at 2822.255 kb on - strand, within Rv2506at 2822.255 kb on - strand, within Rv2506at 2822.355 kb on + strandat 2822.356 kb on - strandat 2822.356 kb on - strandat 2822.356 kb on - strandat 2822.357 kb on + strandat 2822.357 kb on + strandat 2822.358 kb on - strandat 2822.358 kb on - strandat 2822.415 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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2,820,749 + Rv2505c 0.48 -0.2
2,820,862 + Rv2505c 0.55 +0.8
2,820,881 + Rv2505c 0.56 -0.6
2,820,920 + Rv2505c 0.59 +0.4
2,820,945 - Rv2505c 0.60 +0.2
2,821,014 - Rv2505c 0.65 -0.1
2,821,179 - Rv2505c 0.75 -1.1
2,821,242 - Rv2505c 0.78 -0.4
2,821,282 + Rv2505c 0.81 -1.1
2,821,430 + Rv2505c 0.90 +0.3
2,821,557 - -0.0
2,821,557 - +0.3
2,821,616 + -1.1
2,821,647 + +1.9
2,821,648 - +0.5
2,821,648 - -1.0
2,821,658 - +0.9
2,821,672 + +0.5
2,821,898 + Rv2506 0.29 -0.6
2,822,091 + Rv2506 0.58 -2.5
2,822,144 + Rv2506 0.67 -0.6
2,822,255 - Rv2506 0.84 -1.6
2,822,255 - Rv2506 0.84 -3.0
2,822,355 + -1.3
2,822,356 - -1.1
2,822,356 - -1.5
2,822,356 - -2.1
2,822,357 + +2.6
2,822,357 + -0.6
2,822,358 - +0.2
2,822,358 - -1.6
2,822,415 - -0.3

Or see this region's nucleotide sequence