Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2429

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2427A and Rv2428 are separated by 105 nucleotidesRv2428 and Rv2429 are separated by 25 nucleotidesRv2429 and Rv2430c overlap by 4 nucleotidesRv2430c and Rv2431c are separated by 46 nucleotides Rv2427A: Rv2427A - 'Transcriptional regulator OxyR', pseudogene' pseudogene=unknown transl_table=11, at 2,725,571 to 2,726,087 Rv2427A Rv2428: Rv2428 - Alkyl hydroperoxide reductase C protein AhpC (alkyl hydroperoxidase C), at 2,726,193 to 2,726,780 Rv2428 Rv2429: Rv2429 - Alkyl hydroperoxide reductase D protein AhpD (alkyl hydroperoxidase D), at 2,726,806 to 2,727,339 Rv2429 Rv2430c: Rv2430c - PPE family protein PPE41, at 2,727,336 to 2,727,920 Rv2430c Rv2431c: Rv2431c - PE family protein PE25, at 2,727,967 to 2,728,266 Rv2431c Position (kb) 2726 2727 2728Strain fitness (log2 ratio) -2 -1 0 1 2at 2725.845 kb on + strand, within Rv2427Aat 2726.098 kb on - strandat 2726.292 kb on + strand, within Rv2428at 2726.303 kb on + strand, within Rv2428at 2726.812 kb on - strandat 2726.957 kb on + strand, within Rv2429at 2727.326 kb on + strandat 2727.327 kb on - strandat 2727.327 kb on - strandat 2727.338 kb on - strandat 2727.463 kb on + strand, within Rv2430cat 2727.464 kb on - strand, within Rv2430cat 2727.464 kb on - strand, within Rv2430cat 2727.506 kb on - strand, within Rv2430cat 2727.593 kb on - strand, within Rv2430cat 2727.615 kb on - strand, within Rv2430cat 2727.634 kb on + strand, within Rv2430cat 2727.634 kb on + strand, within Rv2430cat 2727.874 kb on + strandat 2727.875 kb on - strandat 2727.876 kb on + strandat 2727.877 kb on - strandat 2727.877 kb on - strandat 2727.877 kb on - strandat 2727.969 kb on - strandat 2728.007 kb on + strand, within Rv2431cat 2728.007 kb on + strand, within Rv2431cat 2728.008 kb on - strand, within Rv2431cat 2728.008 kb on - strand, within Rv2431cat 2728.008 kb on - strand, within Rv2431cat 2728.008 kb on - strand, within Rv2431cat 2728.008 kb on - strand, within Rv2431cat 2728.083 kb on - strand, within Rv2431cat 2728.094 kb on + strand, within Rv2431c

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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2,725,845 + Rv2427A 0.53 +0.8
2,726,098 - +0.4
2,726,292 + Rv2428 0.17 -0.6
2,726,303 + Rv2428 0.19 +0.8
2,726,812 - -0.5
2,726,957 + Rv2429 0.28 -1.1
2,727,326 + -1.0
2,727,327 - -0.2
2,727,327 - -1.1
2,727,338 - +0.2
2,727,463 + Rv2430c 0.22 -1.3
2,727,464 - Rv2430c 0.22 -2.1
2,727,464 - Rv2430c 0.22 -0.0
2,727,506 - Rv2430c 0.29 +1.1
2,727,593 - Rv2430c 0.44 -0.0
2,727,615 - Rv2430c 0.48 -1.0
2,727,634 + Rv2430c 0.51 +0.1
2,727,634 + Rv2430c 0.51 +0.4
2,727,874 + -0.2
2,727,875 - -0.2
2,727,876 + -1.0
2,727,877 - -0.3
2,727,877 - -0.2
2,727,877 - +0.1
2,727,969 - +1.8
2,728,007 + Rv2431c 0.13 +0.3
2,728,007 + Rv2431c 0.13 -0.2
2,728,008 - Rv2431c 0.14 -0.7
2,728,008 - Rv2431c 0.14 +0.8
2,728,008 - Rv2431c 0.14 +0.5
2,728,008 - Rv2431c 0.14 -0.3
2,728,008 - Rv2431c 0.14 -1.8
2,728,083 - Rv2431c 0.39 +0.1
2,728,094 + Rv2431c 0.42 -1.2

Or see this region's nucleotide sequence