Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2384

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2383c and Rv2384 are separated by 98 nucleotidesRv2384 and Rv2385 are separated by 95 nucleotides Rv2383c: Rv2383c - Phenyloxazoline synthase MbtB (phenyloxazoline synthetase), at 2,671,593 to 2,675,837 Rv2383c Rv2384: Rv2384 - Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase, at 2,675,936 to 2,677,633 Rv2384 Rv2385: Rv2385 - Putative acetyl hydrolase MbtJ, at 2,677,729 to 2,678,649 Rv2385 Position (kb) 2675 2676 2677 2678Strain fitness (log2 ratio) -2 -1 0 1at 2675.054 kb on - strand, within Rv2383cat 2675.054 kb on - strand, within Rv2383cat 2675.089 kb on + strand, within Rv2383cat 2675.122 kb on + strand, within Rv2383cat 2675.163 kb on + strand, within Rv2383cat 2675.825 kb on + strandat 2675.826 kb on - strandat 2675.881 kb on - strandat 2675.909 kb on + strandat 2676.624 kb on - strand, within Rv2384at 2676.680 kb on + strand, within Rv2384at 2676.680 kb on + strand, within Rv2384at 2676.681 kb on - strand, within Rv2384at 2677.179 kb on - strand, within Rv2384at 2677.229 kb on + strand, within Rv2384at 2677.906 kb on + strand, within Rv2385at 2677.907 kb on - strand, within Rv2385at 2677.907 kb on - strand, within Rv2385at 2677.957 kb on + strand, within Rv2385at 2677.957 kb on + strand, within Rv2385at 2677.958 kb on - strand, within Rv2385at 2677.958 kb on - strand, within Rv2385at 2677.960 kb on + strand, within Rv2385at 2677.960 kb on + strand, within Rv2385at 2677.965 kb on - strand, within Rv2385at 2677.965 kb on - strand, within Rv2385at 2677.979 kb on - strand, within Rv2385at 2678.080 kb on + strand, within Rv2385at 2678.080 kb on + strand, within Rv2385at 2678.365 kb on + strand, within Rv2385

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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2,675,054 - Rv2383c 0.82 -1.3
2,675,054 - Rv2383c 0.82 -0.4
2,675,089 + Rv2383c 0.82 -1.5
2,675,122 + Rv2383c 0.83 +0.0
2,675,163 + Rv2383c 0.84 +1.1
2,675,825 + +1.2
2,675,826 - -0.6
2,675,881 - -1.0
2,675,909 + +0.2
2,676,624 - Rv2384 0.41 -1.1
2,676,680 + Rv2384 0.44 -0.1
2,676,680 + Rv2384 0.44 -1.2
2,676,681 - Rv2384 0.44 +0.2
2,677,179 - Rv2384 0.73 -0.3
2,677,229 + Rv2384 0.76 -1.9
2,677,906 + Rv2385 0.19 -0.6
2,677,907 - Rv2385 0.19 -0.3
2,677,907 - Rv2385 0.19 +0.1
2,677,957 + Rv2385 0.25 -0.4
2,677,957 + Rv2385 0.25 -0.1
2,677,958 - Rv2385 0.25 +0.1
2,677,958 - Rv2385 0.25 -0.5
2,677,960 + Rv2385 0.25 -0.8
2,677,960 + Rv2385 0.25 -0.1
2,677,965 - Rv2385 0.26 +0.3
2,677,965 - Rv2385 0.26 +0.7
2,677,979 - Rv2385 0.27 +0.0
2,678,080 + Rv2385 0.38 +0.1
2,678,080 + Rv2385 0.38 -0.4
2,678,365 + Rv2385 0.69 -0.4

Or see this region's nucleotide sequence