Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0955

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0954 and Rv0955 are separated by 39 nucleotidesRv0955 and Rv0956 are separated by 115 nucleotidesRv0956 and Rv0957 overlap by 4 nucleotides Rv0954: Rv0954 - Probable conserved transmembrane protein, at 1,065,127 to 1,066,038 Rv0954 Rv0955: Rv0955 - Probable conserved integral membrane protein, at 1,066,078 to 1,067,445 Rv0955 Rv0956: Rv0956 - Probable 5'-phosphoribosylglycinamide formyltransferase PurN (GART) (gar transformylase) (5'-phosphoribosylglycinamide transformylase), at 1,067,561 to 1,068,208 Rv0956 Rv0957: Rv0957 - Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC), at 1,068,205 to 1,069,776 Rv0957 Position (kb) 1066 1067 1068Strain fitness (log2 ratio) -1 0 1at 1065.233 kb on + strand, within Rv0954at 1065.234 kb on - strand, within Rv0954at 1065.281 kb on - strand, within Rv0954at 1065.440 kb on + strand, within Rv0954at 1065.440 kb on + strand, within Rv0954at 1065.646 kb on + strand, within Rv0954at 1065.697 kb on + strand, within Rv0954at 1065.698 kb on - strand, within Rv0954at 1066.793 kb on - strand, within Rv0955at 1067.075 kb on + strand, within Rv0955at 1067.183 kb on + strand, within Rv0955at 1067.288 kb on + strand, within Rv0955at 1067.388 kb on + strandat 1067.491 kb on + strandat 1067.549 kb on + strandat 1067.549 kb on + strandat 1068.201 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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1,065,233 + Rv0954 0.12 -0.3
1,065,234 - Rv0954 0.12 -1.2
1,065,281 - Rv0954 0.17 -1.4
1,065,440 + Rv0954 0.34 -0.6
1,065,440 + Rv0954 0.34 +0.1
1,065,646 + Rv0954 0.57 -1.2
1,065,697 + Rv0954 0.62 -0.8
1,065,698 - Rv0954 0.63 -0.8
1,066,793 - Rv0955 0.52 -0.7
1,067,075 + Rv0955 0.73 -1.1
1,067,183 + Rv0955 0.81 -0.8
1,067,288 + Rv0955 0.88 +0.7
1,067,388 + -0.2
1,067,491 + -0.4
1,067,549 + +0.4
1,067,549 + +1.2
1,068,201 + -0.2

Or see this region's nucleotide sequence