Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0413

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0412c and Rv0413 are separated by 93 nucleotidesRv0413 and Rv0414c overlap by 17 nucleotidesRv0414c and Rv0415 are separated by 129 nucleotides Rv0412c: Rv0412c - Possible conserved membrane protein, at 498,300 to 499,619 Rv0412c Rv0413: Rv0413 - Possible mutator protein MutT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase), at 499,713 to 500,366 Rv0413 Rv0414c: Rv0414c - Thiamine-phosphate pyrophosphorylase ThiE (TMP pyrophosphorylase) (TMP-PPASE) (thiamine-phosphate synthase), at 500,350 to 501,018 Rv0414c Rv0415: Rv0415 - Possible thiamine biosynthesis oxidoreductase ThiO, at 501,148 to 502,170 Rv0415 Position (kb) 499 500 501Strain fitness (log2 ratio) -1 0 1 2at 499.627 kb on - strandat 499.627 kb on - strandat 499.700 kb on + strandat 499.701 kb on - strandat 499.701 kb on - strandat 499.701 kb on - strandat 499.701 kb on - strandat 499.707 kb on - strandat 499.707 kb on - strandat 499.735 kb on - strandat 499.735 kb on - strandat 500.064 kb on + strand, within Rv0413at 500.065 kb on - strand, within Rv0413at 500.065 kb on - strand, within Rv0413at 500.065 kb on - strand, within Rv0413at 500.171 kb on - strand, within Rv0413at 500.304 kb on - strandat 500.343 kb on - strandat 500.343 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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499,627 - -1.2
499,627 - -1.2
499,700 + +2.5
499,701 - -0.1
499,701 - -0.5
499,701 - -0.4
499,701 - -0.2
499,707 - -0.0
499,707 - +0.4
499,735 - -0.5
499,735 - -1.4
500,064 + Rv0413 0.54 -0.6
500,065 - Rv0413 0.54 +0.2
500,065 - Rv0413 0.54 -1.1
500,065 - Rv0413 0.54 -1.0
500,171 - Rv0413 0.70 -0.9
500,304 - -0.0
500,343 - +0.1
500,343 - -1.5

Or see this region's nucleotide sequence