Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0390

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0389 and Rv0390 overlap by 4 nucleotidesRv0390 and Rv0391 overlap by 4 nucleotides Rv0389: Rv0389 - Probable phosphoribosylglycinamide formyltransferase 2 PurT (GART 2) (gar transformylase 2) (5'-phosphoribosylglycinamide transformylase 2) (formate-dependent gar transformylase), at 468,335 to 469,594 Rv0389 Rv0390: Rv0390 - Conserved protein, at 469,591 to 470,013 Rv0390 Rv0391: Rv0391 - Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase), at 470,010 to 471,230 Rv0391 Position (kb) 469 470 471Strain fitness (log2 ratio) -2 -1 0 1at 469.069 kb on + strand, within Rv0389at 469.070 kb on - strand, within Rv0389at 469.070 kb on - strand, within Rv0389at 469.235 kb on + strand, within Rv0389at 469.235 kb on + strand, within Rv0389at 469.235 kb on + strand, within Rv0389at 469.236 kb on - strand, within Rv0389at 469.597 kb on + strandat 469.598 kb on - strandat 469.608 kb on + strandat 469.738 kb on + strand, within Rv0390at 469.738 kb on + strand, within Rv0390at 469.738 kb on + strand, within Rv0390at 469.738 kb on + strand, within Rv0390at 469.839 kb on + strand, within Rv0390at 469.916 kb on - strand, within Rv0390at 469.916 kb on - strand, within Rv0390at 470.130 kb on + strandat 470.146 kb on - strand, within Rv0391at 470.152 kb on - strand, within Rv0391at 470.202 kb on + strand, within Rv0391at 470.202 kb on + strand, within Rv0391at 470.203 kb on - strand, within Rv0391at 470.208 kb on + strand, within Rv0391at 470.208 kb on + strand, within Rv0391at 470.721 kb on + strand, within Rv0391at 470.929 kb on - strand, within Rv0391

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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469,069 + Rv0389 0.58 -1.3
469,070 - Rv0389 0.58 +0.9
469,070 - Rv0389 0.58 -0.4
469,235 + Rv0389 0.71 +0.2
469,235 + Rv0389 0.71 -0.9
469,235 + Rv0389 0.71 +0.2
469,236 - Rv0389 0.72 +0.2
469,597 + -1.0
469,598 - -0.8
469,608 + -1.8
469,738 + Rv0390 0.35 -2.5
469,738 + Rv0390 0.35 +0.2
469,738 + Rv0390 0.35 +1.1
469,738 + Rv0390 0.35 -0.9
469,839 + Rv0390 0.59 -0.9
469,916 - Rv0390 0.77 -1.6
469,916 - Rv0390 0.77 +0.2
470,130 + -1.6
470,146 - Rv0391 0.11 -1.1
470,152 - Rv0391 0.12 -1.7
470,202 + Rv0391 0.16 -1.6
470,202 + Rv0391 0.16 -0.5
470,203 - Rv0391 0.16 -2.4
470,208 + Rv0391 0.16 -1.3
470,208 + Rv0391 0.16 -1.5
470,721 + Rv0391 0.58 -2.3
470,929 - Rv0391 0.75 -1.1

Or see this region's nucleotide sequence