Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0056

Experiment: propionate (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0053 and Rv0054 are separated by 103 nucleotidesRv0054 and Rv0055 are separated by 41 nucleotidesRv0055 and Rv0056 are separated by 32 nucleotidesRv0056 and Rv0057 are separated by 28 nucleotidesRv0057 and Rv0058 overlap by 22 nucleotides Rv0053: Rv0053 - 30S ribosomal protein S6 RpsF, at 58,192 to 58,482 Rv0053 Rv0054: Rv0054 - Single-strand binding protein Ssb (helix-destabilizing protein), at 58,586 to 59,080 Rv0054 Rv0055: Rv0055 - 30S ribosomal protein S18-1 RpsR1, at 59,122 to 59,376 Rv0055 Rv0056: Rv0056 - 50S ribosomal protein L9 RplI, at 59,409 to 59,867 Rv0056 Rv0057: Rv0057 - Hypothetical protein, at 59,896 to 60,417 Rv0057 Rv0058: Rv0058 - Probable replicative DNA helicase DnaB, at 60,396 to 63,020 Rv0058 Position (kb) 59 60Strain fitness (log2 ratio) -2 -1 0 1at 58.480 kb on + strandat 58.526 kb on + strandat 59.406 kb on - strandat 59.585 kb on - strand, within Rv0056at 59.593 kb on + strand, within Rv0056at 60.126 kb on + strand, within Rv0057at 60.211 kb on + strand, within Rv0057at 60.256 kb on + strand, within Rv0057at 60.273 kb on + strand, within Rv0057at 60.334 kb on + strand, within Rv0057at 60.334 kb on + strand, within Rv0057at 60.334 kb on + strand, within Rv0057

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Per-strain Table

Position Strand Gene LocusTag Fraction propionate (C)
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58,480 + -0.1
58,526 + -0.8
59,406 - +1.2
59,585 - Rv0056 0.38 -2.3
59,593 + Rv0056 0.40 -1.7
60,126 + Rv0057 0.44 -1.1
60,211 + Rv0057 0.60 -0.6
60,256 + Rv0057 0.69 +0.3
60,273 + Rv0057 0.72 +0.6
60,334 + Rv0057 0.84 -1.0
60,334 + Rv0057 0.84 -0.3
60,334 + Rv0057 0.84 -0.0

Or see this region's nucleotide sequence