Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2335

Experiment: Glycerol (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2334 and Rv2335 are separated by 3 nucleotidesRv2335 and Rv2336 are separated by 415 nucleotides Rv2334: Rv2334 - Cysteine synthase a CysK1 (O-acetylserine sulfhydrylase A) (O-acetylserine (thiol)-lyase A) (CSASE A), at 2,608,796 to 2,609,728 Rv2334 Rv2335: Rv2335 - Probable serine acetyltransferase CysE (sat), at 2,609,732 to 2,610,421 Rv2335 Rv2336: Rv2336 - Hypothetical protein, at 2,610,837 to 2,611,805 Rv2336 Position (kb) 2609 2610 2611Strain fitness (log2 ratio) -1 0 1at 2609.503 kb on - strand, within Rv2334at 2609.727 kb on - strandat 2609.928 kb on + strand, within Rv2335at 2609.929 kb on - strand, within Rv2335at 2609.929 kb on - strand, within Rv2335at 2609.932 kb on + strand, within Rv2335at 2610.427 kb on + strandat 2610.486 kb on + strandat 2610.574 kb on + strandat 2610.574 kb on + strandat 2610.770 kb on + strandat 2610.771 kb on - strandat 2610.783 kb on - strandat 2611.010 kb on - strand, within Rv2336at 2611.010 kb on - strand, within Rv2336at 2611.010 kb on - strand, within Rv2336at 2611.078 kb on - strand, within Rv2336at 2611.078 kb on - strand, within Rv2336at 2611.099 kb on - strand, within Rv2336at 2611.196 kb on - strand, within Rv2336at 2611.197 kb on + strand, within Rv2336at 2611.198 kb on - strand, within Rv2336

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycerol (C)
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2,609,503 - Rv2334 0.76 -0.2
2,609,727 - +1.0
2,609,928 + Rv2335 0.28 -0.2
2,609,929 - Rv2335 0.29 -0.0
2,609,929 - Rv2335 0.29 -1.3
2,609,932 + Rv2335 0.29 -1.1
2,610,427 + -0.2
2,610,486 + +0.0
2,610,574 + -0.4
2,610,574 + -0.2
2,610,770 + -0.5
2,610,771 - -1.0
2,610,783 - -0.1
2,611,010 - Rv2336 0.18 -0.3
2,611,010 - Rv2336 0.18 +0.1
2,611,010 - Rv2336 0.18 +0.8
2,611,078 - Rv2336 0.25 -0.5
2,611,078 - Rv2336 0.25 +0.0
2,611,099 - Rv2336 0.27 +0.2
2,611,196 - Rv2336 0.37 +0.7
2,611,197 + Rv2336 0.37 -0.2
2,611,198 - Rv2336 0.37 -0.6

Or see this region's nucleotide sequence