Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3909 and Rv3910 overlap by 4 nucleotides Rv3910 and Rv3911 are separated by 34 nucleotides Rv3911 and Rv3912 are separated by 15 nucleotides
Rv3909: Rv3909 - Conserved protein, at 4,394,192 to 4,396,600
Rv3909
Rv3910: Rv3910 - Probable conserved transmembrane protein, at 4,396,597 to 4,400,151
Rv3910
Rv3911: Rv3911 - Possible alternative RNA polymerase sigma factor SigM, at 4,400,186 to 4,400,854
Rv3911
Rv3912: Rv3912 - Hypothetical alanine rich protein, at 4,400,870 to 4,401,634
Rv3912
Position (kb)
4396
4397
4398
4399
4400
4401 Strain fitness (log2 ratio)
-1
0
1 at 4398.331 kb on + strand, within Rv3910 at 4398.752 kb on + strand, within Rv3910 at 4398.752 kb on + strand, within Rv3910 at 4399.819 kb on + strand at 4399.820 kb on - strand at 4399.843 kb on - strand at 4400.082 kb on + strand at 4400.082 kb on + strand at 4400.185 kb on + strand at 4400.204 kb on + strand at 4400.325 kb on + strand, within Rv3911 at 4400.326 kb on - strand, within Rv3911 at 4400.326 kb on - strand, within Rv3911 at 4400.326 kb on - strand, within Rv3911 at 4400.520 kb on + strand, within Rv3911 at 4400.520 kb on + strand, within Rv3911 at 4400.798 kb on - strand at 4400.798 kb on - strand at 4401.135 kb on + strand, within Rv3912 at 4401.136 kb on - strand, within Rv3912 at 4401.136 kb on - strand, within Rv3912
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 4,398,331 + Rv3910 0.49 -0.5 4,398,752 + Rv3910 0.61 -0.5 4,398,752 + Rv3910 0.61 -1.0 4,399,819 + -1.7 4,399,820 - +0.8 4,399,843 - -0.5 4,400,082 + -1.6 4,400,082 + -0.4 4,400,185 + +1.2 4,400,204 + -0.1 4,400,325 + Rv3911 0.21 -0.1 4,400,326 - Rv3911 0.21 +0.0 4,400,326 - Rv3911 0.21 +1.5 4,400,326 - Rv3911 0.21 +0.1 4,400,520 + Rv3911 0.50 -0.5 4,400,520 + Rv3911 0.50 -0.4 4,400,798 - -1.0 4,400,798 - -0.2 4,401,135 + Rv3912 0.35 -0.6 4,401,136 - Rv3912 0.35 -0.2 4,401,136 - Rv3912 0.35 +0.3
Or see this region's nucleotide sequence