Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2950c

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
3,299,742	+		Rv2948c	0.90	-0.8
3,299,742	+		Rv2948c	0.90	+0.5
3,299,878	+				+0.1
3,299,878	+				-0.2
3,299,879	-				+0.2
3,299,896	+				-0.2
3,299,896	+				-0.0
3,299,897	-				-0.7
3,299,957	-				-0.3
3,300,138	-		Rv2949c	0.28	-1.1
3,300,262	+		Rv2949c	0.48	-0.3
3,300,339	+		Rv2949c	0.61	+0.4
3,300,344	-		Rv2949c	0.62	-0.3
3,300,586	-				+0.4
3,300,688	+				-0.2
3,300,743	+				+0.1
3,300,924	+		Rv2950c	0.18	+1.8
3,301,215	+		Rv2950c	0.33	+0.8
3,301,215	+		Rv2950c	0.33	+0.1
3,301,215	+		Rv2950c	0.33	+1.1
3,301,215	+		Rv2950c	0.33	+0.0
3,301,216	-		Rv2950c	0.33	-0.3
3,301,216	-		Rv2950c	0.33	-0.7
3,301,284	+		Rv2950c	0.37	-0.4
3,301,285	-		Rv2950c	0.37	-0.0
3,301,285	-		Rv2950c	0.37	-0.5
3,301,335	+		Rv2950c	0.40	-2.2
3,301,336	-		Rv2950c	0.40	+0.2
3,301,360	-		Rv2950c	0.41	-0.6
3,301,437	-		Rv2950c	0.45	-0.2
3,301,752	-		Rv2950c	0.62	+1.0
3,301,827	+		Rv2950c	0.66	-0.0
3,301,827	+		Rv2950c	0.66	-0.2
3,301,828	-		Rv2950c	0.66	+0.8
3,301,836	+		Rv2950c	0.67	+0.6
3,301,837	-		Rv2950c	0.67	-0.1
3,301,959	+		Rv2950c	0.73	+0.4
3,301,959	+		Rv2950c	0.73	-0.4
3,301,960	-		Rv2950c	0.73	-0.3
3,302,121	+		Rv2950c	0.82	+0.1
3,302,172	+		Rv2950c	0.85	-0.9
3,302,172	+		Rv2950c	0.85	+3.4
3,302,172	+		Rv2950c	0.85	+0.7
3,302,173	-		Rv2950c	0.85	+0.6
3,302,262	+		Rv2950c	0.90	+0.0
3,302,263	-		Rv2950c	0.90	+0.2
3,302,278	-				-0.3
3,302,296	-				-0.5
3,302,315	+				-0.2
3,302,316	-				-0.3
3,302,344	+				-0.1
3,302,344	+				+0.3
3,302,345	-				+0.2
3,302,471	-				-0.1
3,302,471	-				-0.2
3,302,471	-				-0.2
3,302,531	-				+0.5
3,302,539	+				-0.2
3,302,539	+				-0.1
3,302,539	+				+0.0
3,302,540	-				-1.8
3,302,540	-				-0.0
3,302,540	-				-0.3
3,302,540	-				+0.5
3,302,585	+				-0.5
3,302,585	+				-0.3
3,302,585	+				-1.8
3,302,586	-				-0.4
3,302,586	-				+1.8
3,302,592	+				-0.1
3,302,593	-				+1.8
3,302,613	+				-1.7
3,302,614	-				+0.4
3,302,698	-				+0.0
3,302,698	-				-0.3
3,302,698	-				+0.9
3,302,703	+				-2.1
3,302,704	-				+0.3
3,303,206	+				-0.5
3,303,236	-		Rv2951c	0.12	-2.3
3,303,285	+		Rv2951c	0.16	+0.2
3,303,286	-		Rv2951c	0.16	+1.1
3,303,311	+		Rv2951c	0.18	-0.1
3,303,312	-		Rv2951c	0.18	+1.4
3,303,422	-		Rv2951c	0.28	-0.1
3,303,422	-		Rv2951c	0.28	-0.5