Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2772c

Experiment: 7H9 with Clofazimine 0.45 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2770c and Rv2771c are separated by 123 nucleotidesRv2771c and Rv2772c are separated by 85 nucleotidesRv2772c and Rv2773c are separated by 11 nucleotidesRv2773c and Rv2774c are separated by 10 nucleotides Rv2770c: Rv2770c - PPE family protein PPE44, at 3,079,309 to 3,080,457 Rv2770c Rv2771c: Rv2771c - Conserved hypothetical protein, at 3,080,581 to 3,081,033 Rv2771c Rv2772c: Rv2772c - Probable conserved transmembrane protein, at 3,081,119 to 3,081,592 Rv2772c Rv2773c: Rv2773c - Dihydrodipicolinate reductase DapB (DHPR), at 3,081,604 to 3,082,341 Rv2773c Rv2774c: Rv2774c - Hypothetical protein, at 3,082,352 to 3,082,756 Rv2774c Position (kb) 3081 3082Strain fitness (log2 ratio) -3 -2 -1 0 1at 3080.243 kb on + strand, within Rv2770cat 3080.243 kb on + strand, within Rv2770cat 3080.243 kb on + strand, within Rv2770cat 3080.244 kb on - strand, within Rv2770cat 3080.244 kb on - strand, within Rv2770cat 3080.244 kb on - strand, within Rv2770cat 3080.244 kb on - strand, within Rv2770cat 3080.356 kb on + strandat 3080.356 kb on + strandat 3080.357 kb on - strandat 3080.357 kb on - strandat 3080.357 kb on - strandat 3080.411 kb on + strandat 3080.412 kb on - strandat 3080.412 kb on - strandat 3080.441 kb on - strandat 3080.518 kb on + strandat 3080.590 kb on + strandat 3080.591 kb on - strandat 3080.665 kb on + strand, within Rv2771cat 3080.666 kb on - strand, within Rv2771cat 3080.756 kb on + strand, within Rv2771cat 3080.798 kb on + strand, within Rv2771cat 3080.799 kb on - strand, within Rv2771cat 3080.801 kb on + strand, within Rv2771cat 3080.802 kb on - strand, within Rv2771cat 3080.802 kb on - strand, within Rv2771cat 3081.097 kb on + strandat 3081.149 kb on + strandat 3081.149 kb on + strandat 3081.388 kb on - strand, within Rv2772cat 3081.528 kb on + strand, within Rv2772cat 3081.573 kb on + strandat 3081.573 kb on + strandat 3081.574 kb on - strandat 3082.454 kb on - strand, within Rv2774cat 3082.454 kb on - strand, within Rv2774c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL
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3,080,243 + Rv2770c 0.81 -0.7
3,080,243 + Rv2770c 0.81 -0.1
3,080,243 + Rv2770c 0.81 +0.1
3,080,244 - Rv2770c 0.81 -1.4
3,080,244 - Rv2770c 0.81 -0.3
3,080,244 - Rv2770c 0.81 +0.5
3,080,244 - Rv2770c 0.81 +0.2
3,080,356 + +0.3
3,080,356 + -0.3
3,080,357 - +0.9
3,080,357 - -0.6
3,080,357 - -0.4
3,080,411 + -0.4
3,080,412 - -0.6
3,080,412 - -0.1
3,080,441 - -0.8
3,080,518 + -3.2
3,080,590 + +0.3
3,080,591 - -1.0
3,080,665 + Rv2771c 0.19 -0.6
3,080,666 - Rv2771c 0.19 -0.1
3,080,756 + Rv2771c 0.39 -0.4
3,080,798 + Rv2771c 0.48 -0.2
3,080,799 - Rv2771c 0.48 -0.6
3,080,801 + Rv2771c 0.49 -0.6
3,080,802 - Rv2771c 0.49 +0.5
3,080,802 - Rv2771c 0.49 +0.6
3,081,097 + -1.3
3,081,149 + +1.5
3,081,149 + -1.0
3,081,388 - Rv2772c 0.57 +0.7
3,081,528 + Rv2772c 0.86 +0.7
3,081,573 + +0.7
3,081,573 + +0.3
3,081,574 - -1.2
3,082,454 - Rv2774c 0.25 -0.5
3,082,454 - Rv2774c 0.25 +1.2

Or see this region's nucleotide sequence