Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2688c

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
3,004,064	-				+0.1
3,004,213	+		Rv2687c	0.25	-0.4
3,004,214	-		Rv2687c	0.25	-0.3
3,004,604	-		Rv2687c	0.80	-0.3
3,004,662	-		Rv2687c	0.88	+1.2
3,004,707	+				+0.1
3,004,805	-				-0.9
3,005,211	+		Rv2688c	0.51	+0.3
3,005,212	-		Rv2688c	0.52	+2.3
3,005,222	+		Rv2688c	0.53	-0.1
3,005,223	-		Rv2688c	0.53	+0.2
3,005,292	+		Rv2688c	0.60	-0.0
3,005,293	-		Rv2688c	0.60	+0.4
3,005,322	+		Rv2688c	0.64	-0.6
3,005,380	-		Rv2688c	0.70	+0.6
3,005,498	+		Rv2688c	0.83	-0.7
3,005,499	-		Rv2688c	0.83	+0.1
3,005,499	-		Rv2688c	0.83	-0.7
3,005,730	+				+1.8
3,005,772	+				+0.2
3,005,772	+				-0.3
3,005,773	-				+0.1
3,005,775	+				-0.5
3,005,775	+				-0.9
3,005,789	+				+0.6
3,005,790	-				-0.5
3,005,847	-				+1.5
3,005,847	-				+0.8
3,005,882	+				+0.3
3,005,882	+				-0.1
3,005,883	-				+0.9
3,005,883	-				+0.1
3,005,988	+		Rv2689c	0.12	-0.5
3,005,988	+		Rv2689c	0.12	-0.8
3,005,988	+		Rv2689c	0.12	+0.6
3,005,989	-		Rv2689c	0.12	-0.0
3,005,989	-		Rv2689c	0.12	-0.7
3,005,989	-		Rv2689c	0.12	-0.3
3,005,989	-		Rv2689c	0.12	-0.1
3,005,992	+		Rv2689c	0.12	-0.9
3,005,992	+		Rv2689c	0.12	-0.9
3,005,993	-		Rv2689c	0.12	+0.3
3,005,993	-		Rv2689c	0.12	+0.8
3,005,993	-		Rv2689c	0.12	-0.2
3,005,993	-		Rv2689c	0.12	+1.4
3,005,993	-		Rv2689c	0.12	-0.5
3,005,993	-		Rv2689c	0.12	-0.2
3,006,323	+		Rv2689c	0.39	+0.2
3,006,323	+		Rv2689c	0.39	+0.0
3,006,448	-		Rv2689c	0.50	+1.3
3,006,512	+		Rv2689c	0.55	-0.2
3,006,512	+		Rv2689c	0.55	-0.3
3,006,513	-		Rv2689c	0.55	+0.1
3,006,556	+		Rv2689c	0.58	+0.3
3,006,614	+		Rv2689c	0.63	-0.4