Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2592c and Rv2593c overlap by 4 nucleotides Rv2593c and Rv2594c overlap by 4 nucleotides Rv2594c and Rv2595 are separated by 108 nucleotides Rv2595 and Rv2596 overlap by 4 nucleotides Rv2596 and Rv2597 are separated by 216 nucleotides
Rv2592c: Rv2592c - Probable holliday junction DNA helicase RuvB, at 2,923,199 to 2,924,233
Rv2592c
Rv2593c: Rv2593c - Probable holliday junction DNA helicase RuvA, at 2,924,230 to 2,924,820
Rv2593c
Rv2594c: Rv2594c - Probable crossover junction endodeoxyribonuclease RuvC (holliday junction nuclease) (holliday junction resolvase), at 2,924,817 to 2,925,383
Rv2594c
Rv2595: Rv2595 - Possible antitoxin VapB40, at 2,925,492 to 2,925,737
Rv2595
Rv2596: Rv2596 - Possible toxin VapC40. Contains PIN domain., at 2,925,734 to 2,926,138
Rv2596
Rv2597: Rv2597 - Probable membrane protein, at 2,926,355 to 2,926,975
Rv2597
Position (kb)
2924
2925
2926 Strain fitness (log2 ratio)
-2
-1
0
1 at 2925.462 kb on + strand at 2925.463 kb on - strand at 2925.857 kb on + strand, within Rv2596 at 2925.858 kb on - strand, within Rv2596 at 2925.892 kb on + strand, within Rv2596 at 2925.892 kb on + strand, within Rv2596 at 2925.917 kb on + strand, within Rv2596 at 2925.918 kb on - strand, within Rv2596 at 2925.944 kb on + strand, within Rv2596 at 2926.022 kb on + strand, within Rv2596 at 2926.101 kb on - strand at 2926.286 kb on + strand at 2926.287 kb on - strand at 2926.291 kb on + strand at 2926.350 kb on + strand at 2926.350 kb on + strand at 2926.351 kb on - strand at 2926.351 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 2,925,462 + -0.0 2,925,463 - -0.3 2,925,857 + Rv2596 0.30 +0.2 2,925,858 - Rv2596 0.31 +1.5 2,925,892 + Rv2596 0.39 -0.3 2,925,892 + Rv2596 0.39 +0.3 2,925,917 + Rv2596 0.45 -0.2 2,925,918 - Rv2596 0.45 +0.2 2,925,944 + Rv2596 0.52 +0.3 2,926,022 + Rv2596 0.71 -2.0 2,926,101 - -0.5 2,926,286 + -0.3 2,926,287 - +0.7 2,926,291 + -0.6 2,926,350 + -0.6 2,926,350 + -0.2 2,926,351 - -0.2 2,926,351 - -0.4
Or see this region's nucleotide sequence