Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2476c

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
2,776,641	+		Rv2474c	0.50	+0.6
2,776,977	-				-0.1
2,777,000	+				-1.4
2,777,001	-				-0.8
2,777,211	-		Rv2475c	0.57	-0.4
2,777,274	+		Rv2475c	0.72	+1.0
2,777,336	+		Rv2475c	0.87	-0.5
2,777,336	+		Rv2475c	0.87	-1.5
2,777,336	+		Rv2475c	0.87	-0.1
2,777,336	+		Rv2475c	0.87	-1.2
2,777,611	-				-1.4
2,777,735	-				-0.3
2,777,830	+				+0.2
2,777,996	-		Rv2476c	0.12	+0.2
2,778,137	-		Rv2476c	0.15	+2.8
2,778,193	+		Rv2476c	0.17	-0.2
2,778,515	-		Rv2476c	0.23	+0.4
2,779,505	+		Rv2476c	0.43	-1.6
2,779,506	-		Rv2476c	0.43	-2.0
2,779,531	+		Rv2476c	0.44	+0.2
2,779,531	+		Rv2476c	0.44	-1.1
2,779,639	+		Rv2476c	0.46	-2.6
2,779,959	+		Rv2476c	0.53	+1.0
2,780,728	+		Rv2476c	0.69	-1.1
2,781,043	+		Rv2476c	0.75	+0.8
2,781,386	-		Rv2476c	0.82	+0.4
2,781,404	-		Rv2476c	0.82	-0.6
2,782,061	-				+0.3
2,782,160	-				-0.6
2,782,172	-				-0.2
2,782,361	+				+1.1
2,782,361	+				+1.8
2,782,362	-				+0.5
2,782,362	-				-0.9