Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2249c

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
2,522,304	+				+0.2
2,522,578	-		Rv2248	0.27	+0.0
2,522,736	+		Rv2248	0.46	+1.8
2,522,827	-		Rv2248	0.57	-0.4
2,523,328	-				-0.1
2,523,620	+		Rv2249c	0.24	-1.0
2,523,742	+		Rv2249c	0.32	-0.7
2,523,762	-		Rv2249c	0.34	-0.5
2,523,816	+		Rv2249c	0.37	-1.6
2,524,560	-		Rv2249c	0.85	-0.6
2,524,663	+				+1.8
2,524,795	+				-0.5
2,524,796	-				+1.3
2,524,796	-				+1.6
2,524,815	-				-1.2
2,525,020	+		Rv2250c	0.41	+1.0
2,525,103	+		Rv2250c	0.56	-0.3
2,525,594	+				-1.1